Metabolic reprogramming is a hallmark of solid cancers. Macrophages as major constituents
of immune system take important roles in regulation of tumorigenesis. Pro-tumor M2 …

Macrophages are pivotal in the initiation and development of atherosclerotic cardiovascular
diseases. Recent studies have reinforced the importance of mitochondria in metabolic and …

Aims: Reactive oxygen species (ROS) are highly reactive molecules generated in different
subcellular sites or compartments, including endosomes via the NOX2-containing …

Aging promotes numerous intracellular changes in T cells that impact their effector function.
Our data show that aging promotes an increase in the localization of STAT3 to the …

Excessive activation of pro‐inflammatory M1 macrophages following acute myocardial
infarction (MI) aggravates adverse cardiac remodelling and heart dysfunction. There are two …

ABSTRACT Introduction: Traumatic Brain Injury (TBI) is a leading cause of death and
disability in young people, affecting 69 million people annually, worldwide. The initial trauma …

The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-
methylsulfinyloctyl isothiocyanate ((R)-8-OITC), present in watercress, based on the “DAG …

The head and neck tumor microenvironment (TME) is highly infiltrated with macrophages.
More specifically, tumor-associated macrophages (TAM/M2-like) are one of the most critical …

Legionella pneumophila is the causative agent of Legionnaires' disease, a severe
pneumonia. L. pneumophila injects via a type-IV-secretion-system (T4SS) more than 300 …

Simple Summary Bovine endometritis is characterized by reduced milk production and high
infertility rates, resulting in substantial economic losses for the dairy farming sector …