Hypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular
events, yet the pathophysiological basis of this association is unclear. Disturbed mineral …

Vascular calcification (VC) is strongly associated with all-cause mortality and is an
independent predictor of cardiovascular events. Resulting from its complex, multifaceted …

Many epidemiological studies show a positive connection between cardiovascular diseases
and risk of osteoporosis, suggesting a role of hyperlipidemia and/or hypercholesterolemia in …

Cardiovascular diseases remain the primary cause of death. 1 Myocardial infarction (MI),
angina, and stroke take> 16 million lives every year, but the underlying mechanisms by …

Cardiovascular calcification is a prominent feature of chronic inflammatory disorders—such
as chronic kidney disease, type 2 diabetes mellitus, and atherosclerosis—that associate with …

Recent evidence indicates that saturated fatty acid–induced (SFA-induced) lipotoxicity
contributes to the pathogenesis of cardiovascular and metabolic diseases; however, the …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids in the vessel wall, leading to the formation of an atheroma and eventually to the …

Background Cardiovascular diseases such as atherosclerosis and vascular calcification are
a major cause of death in patients with chronic kidney disease (CKD). Recently, the long …

Previously, we reported that stearate, a saturated fatty acid, promotes osteoblastic
differentiation and mineralization of vascular smooth muscle cells (VSMC). In this study, we …

Fatty acids (FAs) are essential nutrients and main constituents of cell membranes that are
involved in the signaling pathway and associated with health conditions. We investigated if …