Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Clinical and biological characterization of skin pigmentation diversity and its consequences on UV impact
S Del Bino, C Duval, F Bernerd - International journal of molecular …, 2018 - mdpi.com
Skin color diversity is the most variable and noticeable phenotypic trait in humans resulting
from constitutive pigmentation variability. This paper will review the characterization of skin …
from constitutive pigmentation variability. This paper will review the characterization of skin …
Loci associated with skin pigmentation identified in African populations
INTRODUCTION Variation in pigmentation among human populations may reflect local
adaptation to regional light environments, because dark skin is more photoprotective …
adaptation to regional light environments, because dark skin is more photoprotective …
Upper Palaeolithic genomes reveal deep roots of modern Eurasians
ER Jones, G Gonzalez-Fortes, S Connell… - Nature …, 2015 - nature.com
We extend the scope of European palaeogenomics by sequencing the genomes of Late
Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old …
Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old …
Pleistocene North African genomes link near Eastern and sub-Saharan African human populations
North Africa is a key region for understanding human history, but the genetic history of its
people is largely unknown. We present genomic data from seven 15,000-year-old modern …
people is largely unknown. We present genomic data from seven 15,000-year-old modern …
Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers
Prehistoric population structure associated with the transition to an agricultural lifestyle in
Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone …
Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone …
An unexpectedly complex architecture for skin pigmentation in Africans
Approximately 15 genes have been directly associated with skin pigmentation variation in
humans, leading to its characterization as a relatively simple trait. However, by assembling a …
humans, leading to its characterization as a relatively simple trait. However, by assembling a …
Creating artificial human genomes using generative neural networks
Generative models have shown breakthroughs in a wide spectrum of domains due to recent
advancements in machine learning algorithms and increased computational power. Despite …
advancements in machine learning algorithms and increased computational power. Despite …
The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables
NG Jablonski - Pigment Cell & Melanoma Research, 2021 - Wiley Online Library
The primary biological role of human skin pigmentation is as a mediator of penetration of
ultraviolet radiation (UVR) into the deep layers of skin and the cutaneous circulation. Since …
ultraviolet radiation (UVR) into the deep layers of skin and the cutaneous circulation. Since …
Human adaptation to arsenic-rich environments
CM Schlebusch, LM Gattepaille… - Molecular biology …, 2015 - academic.oup.com
Adaptation drives genomic changes; however, evidence of specific adaptations in humans
remains limited. We found that inhabitants of the northern Argentinean Andes, an arid region …
remains limited. We found that inhabitants of the northern Argentinean Andes, an arid region …