Linezolid for drug‐resistant pulmonary tuberculosis
Background Linezolid was recently re‐classified as a Group A drug by the World Health
Organization (WHO) for treatment of multi‐drug resistant tuberculosis (MDR‐TB) and …
Organization (WHO) for treatment of multi‐drug resistant tuberculosis (MDR‐TB) and …
Comorbidities and treatment outcomes in multidrug resistant tuberculosis: a systematic review and meta-analysis
JP Samuels, A Sood, JR Campbell, F Ahmad Khan… - Scientific reports, 2018 - nature.com
Little is known about the impact of comorbidities on multidrug resistant (MDR) and
extensively drug resistant (XDR) tuberculosis (TB) treatment outcomes. We aimed to …
extensively drug resistant (XDR) tuberculosis (TB) treatment outcomes. We aimed to …
Adjunctive host-directed therapy with statins improves tuberculosis-related outcomes in mice
NK Dutta, N Bruiners, MD Zimmerman… - The Journal of …, 2020 - academic.oup.com
Background Tuberculosis (TB) treatment is lengthy and complicated and patients often
develop chronic lung disease. Recent attention has focused on host-directed therapies …
develop chronic lung disease. Recent attention has focused on host-directed therapies …
Multidrug-resistant tuberculosis treatment outcomes in relation to treatment and initial versus acquired second-line drug resistance
JP Cegielski, E Kurbatova… - Clinical Infectious …, 2016 - academic.oup.com
Background. Resistance to second-line drugs develops during treatment of multidrug-
resistant (MDR) tuberculosis, but the impact on treatment outcome has not been determined …
resistant (MDR) tuberculosis, but the impact on treatment outcome has not been determined …
[HTML][HTML] Linezolid-associated neurologic adverse events in patients with multidrug-resistant tuberculosis, France
M Jaspard, N Butel, N El Helali… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Linezolid is one of the most effective drugs for treating multidrug-resistant tuberculosis (MDR
TB), but adverse effects remain problematic. We evaluated 57 MDR TB patients who had …
TB), but adverse effects remain problematic. We evaluated 57 MDR TB patients who had …
[HTML][HTML] New antituberculosis drugs: from clinical trial to programmatic use
G Gualano, S Capone, A Matteelli… - Infectious disease …, 2016 - ncbi.nlm.nih.gov
Abstract Treatment of multidrug-resistant tuberculosis (MDR-TB) cases is challenging
because it relies on second-line drugs that are less potent and more toxic than those used in …
because it relies on second-line drugs that are less potent and more toxic than those used in …
Design, synthesis and anti-Mycobacterium tuberculosis evaluation of new thiazolidin-4-one and thiazolo [3, 2-a][1, 3, 5] triazine derivatives
MH Younis, ER Mohammed, AR Mohamed… - Bioorganic …, 2022 - Elsevier
In response to the urgent need to encounter infection diseases, and upon increasing
concerns about the devastating effects of tuberculosis (TB), the promising thiazolidin-4-one …
concerns about the devastating effects of tuberculosis (TB), the promising thiazolidin-4-one …
Risk factors for poor multidrug-resistant tuberculosis treatment outcomes in Kyiv Oblast, Ukraine
O Aibana, M Bachmaha, V Krasiuk, N Rybak… - BMC infectious …, 2017 - Springer
Background Ukraine is among ten countries with the highest burden of multidrug-resistant
TB (MDR-TB) worldwide. Treatment success rates for MDR-TB in Ukraine remain below …
TB (MDR-TB) worldwide. Treatment success rates for MDR-TB in Ukraine remain below …
Clinical outcome of multidrug-resistant tuberculosis patients receiving standardized second-line treatment regimen in China
C Xu, Y Pang, R Li, Y Ruan, L Wang, M Chen… - Journal of Infection, 2018 - Elsevier
Objectives The aim of this study was to retrospectively analyze the clinical outcome and the
risk factors associated with poor outcome of MDR-TB patients receiving standardized …
risk factors associated with poor outcome of MDR-TB patients receiving standardized …
Time to multidrug-resistant tuberculosis treatment initiation in association with treatment outcomes in Shanghai, China
Y Chen, Z Yuan, X Shen, J Wu, Z Wu… - Antimicrobial agents and …, 2018 - Am Soc Microbiol
In high tuberculosis (TB)-burden countries such as China, the diagnosis of multidrug-
resistant tuberculosis (MDR-TB) using conventional drug susceptibility testing (DST) takes …
resistant tuberculosis (MDR-TB) using conventional drug susceptibility testing (DST) takes …