Circular RNAs (circRNAs) are unique noncoding RNAs that have a closed and stable loop
structure generated through backsplicing. Due to their conservation, stability and tissue …

Current treatment strategies for cancer, especially advanced cancer, are limited and
unsatisfactory. One of the most substantial advances in cancer therapy, in the last decades …

Advances in immunology, immuno-oncology, drug discovery and vaccine development
demand improvements in the capabilities of flow cytometry to allow it to measure more …

Introduction It is now well established that sepsis induces a state of acquired
immunosuppression, with an increased risk of secondary infections that contributes to …

Long non-coding RNAs (lncRNAs) could modulate expression of immune checkpoints
(ICPs) in tumor-immune. However, precise functions in immunity and potential for predicting …

Adenosine (ADO) is a common chemotherapy-associated immune checkpoint that hinders
anti-tumor immunity-mediated efficacy of chemotherapy. Herein, we created a synthetic high …

Over the past decade, cancer immunotherapy has significantly advanced through the
introduction of immune checkpoint inhibitors and the augmentation of adoptive cell transfer …

Recently, considerable interest has emerged in the development of biosensors to detect
biomarkers and immune checkpoints to identify and measure cancer through liquid biopsies …

Introduction Treatment options for patients with malignant pleural effusions (MPE) are limited
due, at least in part, to the unique environment of the pleural space, which drives an …

Following success in cancer immunotherapy, immune checkpoint blockade is emerging as
an exciting potential treatment for some infectious diseases, specifically two chronic viral …