Leveraging a natural murine meiotic drive to suppress invasive populations

L Gierus, A Birand, MD Bunting… - Proceedings of the …, 2022 - National Acad Sciences
Invasive rodents are a major cause of environmental damage and biodiversity loss,
particularly on islands. Unlike insects, genetic biocontrol strategies including population …

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

R Bhattacharjee, LA Jolly, MA Corbett, IC Wee… - Nature …, 2024 - nature.com
We implicated the X-chromosome THOC2 gene, which encodes the largest subunit of the
highly-conserved TREX (Tr anscription-Ex port) complex, in a clinically complex …

A bumpy road ahead for genetic biocontainment

DR George, M Danciu, PW Davenport, MR Lakin… - nature …, 2024 - nature.com
A bumpy road ahead for genetic biocontainment | Nature Communications Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

Investigating the potential of X chromosome shredding for mouse genetic biocontrol

MD Bunting, GI Godahewa, NO McPherson… - Scientific Reports, 2024 - nature.com
CRISPR-Cas9 technology has facilitated development of strategies that can potentially
provide more humane and effective methods to control invasive vertebrate species, such as …

Genetics reveals shifts in reproductive behaviour of the invasive bird parasite Philornis downsi collected from Darwin's finch nests

LK Common, S Kleindorfer, D Colombelli-Négrel… - Biological …, 2023 - Springer
Due to novel or dynamic fluctuations in environmental conditions and resources, host and
parasite relationships can be subject to diverse selection pressures that may lead to …

Critters in the cold: understanding how large-bodied alpine invertebrates are influenced by introduced predators and climate change

AJ Bertoia - 2023 - ourarchive.otago.ac.nz
Invertebrates are the most globally abundant animal group and perform important
ecosystem services like pollination, seed dispersal, and nutrient cycling. Despite all they do …

A framework for identifying fertility gene targets for mammalian pest control

AC Clark, R Edison, K Esvelt, S Kamau… - Molecular ecology …, 2024 - Wiley Online Library
Fertility‐targeted gene drives have been proposed as an ethical genetic approach for
managing wild populations of vertebrate pests for public health and conservation benefit …

Investigating the potential of X shredding for mouse genetic biocontrol

MD Bunting, GI Godahewa, NO McPherson… - bioRxiv, 2023 - biorxiv.org
CRISPR-Cas9 technology has facilitated development of strategies that can potentially
provide more humane and effective methods to control invasive vertebrate species, such as …

[PDF][PDF] Critters in the cold: understanding how large-bodied alpine invertebrates are

AJ Bertoia - ourarchive.otago.ac.nz
Invertebrates are the most globally abundant animal group and perform important
ecosystem services like pollination, seed dispersal, and nutrient cycling. Despite all they do …