Chlamydial intracellular survival strategies

RJ Bastidas, CA Elwell… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the
causative agent of blinding trachoma. Although Chlamydia is protected from humoral …

[HTML][HTML] Infectious agents and neurodegeneration

G De Chiara, ME Marcocci, R Sgarbanti, L Civitelli… - Molecular …, 2012 - Springer
A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …

Evidence for an Association Between Chlamydia psittaci and Ocular Adnexal Lymphomas

AJM Ferreri, M Guidoboni, M Ponzoni… - Journal of the …, 2004 - academic.oup.com
Background: Ocular adnexal lymphomas may be antigen-driven disorders; however, the
source of the putative antigen or antigens is still unknown. Hence, we assessed whether …

Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction

D Heuer, AR Lipinski, N Machuy, A Karlas, A Wehrens… - Nature, 2009 - nature.com
The obligate intracellular bacterium Chlamydia trachomatis survives and replicates within a
membrane-bound vacuole, termed the inclusion, which intercepts host exocytic pathways to …

[HTML][HTML] Exploring the “multiple-hit hypothesis” of neurodegenerative disease: bacterial infection comes up to bat

KL Patrick, SL Bell, CG Weindel… - Frontiers in Cellular and …, 2019 - frontiersin.org
Despite major strides in personalized genomics, it remains poorly understood why
neurodegenerative diseases occur in only a fraction of individuals with a genetic …

The chlamydial inclusion: escape from the endocytic pathway

KA Fields, T Hackstadt - Annual review of cell and …, 2002 - annualreviews.org
▪ Abstract Chlamydiae, bacterial obligate intracellular pathogens, are the etiologic agents of
several human diseases. A large part of the chlamydial intracellular survival strategy …

Chlamydia and apoptosis: life and death decisions of an intracellular pathogen

GI Byrne, DM Ojcius - Nature Reviews Microbiology, 2004 - nature.com
The chlamydiae are important obligate intracellular prokaryotic pathogens that, each year,
are responsible for millions of human infections involving the eye, genital tract, respiratory …

The role of IFN-γ in the outcome of chlamydial infection

ME Rottenberg, A Gigliotti-Rothfuchs… - Current opinion in …, 2002 - Elsevier
Chlamydia are intracellular bacteria which infect many vertebrates, including humans. They
cause a myriad of severe diseases, ranging from asymptomatic infection to pneumonia …

Interactions between bacterial pathogens and mitochondrial cell death pathways

T Rudel, O Kepp, V Kozjak-Pavlovic - Nature Reviews Microbiology, 2010 - nature.com
The modulation of host cell death pathways by bacteria has been recognized as a major
pathogenicity mechanism. Among other strategies, bacterial pathogens can hijack the cell …

Chlamydia Inhibit Host Cell Apoptosis by Degradation of Proapoptotic BH3-only Proteins

SF Fischer, J Vier, S Kirschnek, A Klos… - The Journal of …, 2004 - rupress.org
Chlamydia are obligate intracellular bacteria that replicate in a vacuole inside a host cell.
Chlamydial infection has been shown to protect the host cell against apoptotic stimuli. This is …