Estrogens in male physiology
PS Cooke, MK Nanjappa, CM Ko… - Physiological …, 2017 - journals.physiology.org
Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …
Spermatogenesis in humans and its affecting factors
FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …
into spermatozoa requires the participation of several cell types, hormones, paracrine …
Male infertility due to testicular disorders
Context Male infertility is defined as the inability to conceive following 1 year of regular
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …
Hormonal control of Sertoli cell metabolism regulates spermatogenesis
Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that
reach far beyond the physical support of germ cells, as they are responsible for creating the …
reach far beyond the physical support of germ cells, as they are responsible for creating the …
Environmental exposure to xenoestrogens and oestrogen related cancers: reproductive system, breast, lung, kidney, pancreas, and brain
A Fucic, M Gamulin, Z Ferencic, J Katic… - Environmental …, 2012 - Springer
The role of steroids in carcinogenesis has become a major concern in environmental
protection, biomonitoring, and clinical research. Although historically oestrogen has been …
protection, biomonitoring, and clinical research. Although historically oestrogen has been …
Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells
BACKGROUND: Sertoli cells metabolize glucose producing lactate for developing germ
cells. As insulin regulates glucose uptake and its disturbance/insensitivity is associated with …
cells. As insulin regulates glucose uptake and its disturbance/insensitivity is associated with …
Effects of elevated β-estradiol levels on the functional morphology of the testis-new insights
Elevated estradiol levels are correlated with male infertility. Causes of hyperestrogenism
include diseases of the adrenal cortex, testis or medications affecting the hypothalamus …
include diseases of the adrenal cortex, testis or medications affecting the hypothalamus …
Effects and mechanisms of pyrethroids on male reproductive system
Q Wang, JY Shen, R Zhang, JW Hong, Z Li, Z Ding… - Toxicology, 2020 - Elsevier
Synthetic pyrethroids are used as insecticides in agriculture and a variety of household
applications worldwide. Pyrethroids are widely distributed in all environmental …
applications worldwide. Pyrethroids are widely distributed in all environmental …
Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro
Sertoli cells actively metabolize glucose that is converted into lactate, which is used by
developing germ cells for their energy metabolism. Androgens and oestrogens have general …
developing germ cells for their energy metabolism. Androgens and oestrogens have general …
Influence of 5α‐dihydrotestosterone and 17β‐estradiol on human Sertoli cells metabolism
Sertoli cells metabolize glucose, converting it to lactate that is used by developing germ cells
for their energy metabolism. Androgens and oestrogens have metabolic roles that reach far …
for their energy metabolism. Androgens and oestrogens have metabolic roles that reach far …