[HTML][HTML] Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments
N Ahmad-Mansour, P Loubet, C Pouget… - Toxins, 2021 - mdpi.com
Staphylococcus aureus is a clinically important pathogen that causes a wide range of
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …
Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
[HTML][HTML] A systematic review of plants with antibacterial activities: A taxonomic and phylogenetic perspective
F Chassagne, T Samarakoon, G Porras… - Frontiers in …, 2021 - frontiersin.org
Background: Antimicrobial resistance represents a serious threat to human health across the
globe. The cost of bringing a new antibiotic from discovery to market is high and return on …
globe. The cost of bringing a new antibiotic from discovery to market is high and return on …
[HTML][HTML] Interference in bacterial quorum sensing: a biopharmaceutical perspective
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …
Opportunities for natural products in 21 st century antibiotic discovery
GD Wright - Natural product reports, 2017 - pubs.rsc.org
Natural products and their derivatives are mainstays of our antibiotic drugs, but they are
increasingly in peril. The combination of widespread multidrug resistance in once …
increasingly in peril. The combination of widespread multidrug resistance in once …
Commensal staphylococci influence Staphylococcus aureus skin colonization and disease
CP Parlet, MM Brown, AR Horswill - Trends in microbiology, 2019 - cell.com
Commensal organisms that constitute the skin microbiota play a pivotal role in the
orchestration of cutaneous homeostasis and immune competence. This balance can be …
orchestration of cutaneous homeostasis and immune competence. This balance can be …
Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis
Colonization of the skin by Staphylococcus aureus is associated with exacerbation of atopic
dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome …
dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome …
[HTML][HTML] Coagulase-negative staphylococcal strain prevents Staphylococcus aureus colonization and skin infection by blocking quorum sensing
AE Paharik, CP Parlet, N Chung, DA Todd… - Cell host & …, 2017 - cell.com
Coagulase-negative staphylococci (CoNS) and Staphylococcus aureus are part of the
natural flora of humans and other mammals. We found that spent media from the CoNS …
natural flora of humans and other mammals. We found that spent media from the CoNS …
Natural Products That Target Virulence Factors in Antibiotic-Resistant Staphylococcus aureus
The increase in the incidence of antibiotic-resistant Staphylococcus aureus (S. aureus)
associated infections necessitates the urgent development of novel therapeutic strategies …
associated infections necessitates the urgent development of novel therapeutic strategies …
[HTML][HTML] Targeting ESKAPE pathogens with anti-infective medicinal plants from the Greater Mpigi region in Uganda
Antibiotic resistance poses one of the greatest threats to global health today; conventional
drug therapies are becoming increasingly inefficacious and limited. We identified 16 …
drug therapies are becoming increasingly inefficacious and limited. We identified 16 …