Nonalcoholic fatty liver disease-related hepatocellular carcinoma: the next threat after viral hepatitis

M Salaheldin, H Aly, L Lau, S Afify, M El-Kassas - Diagnostics, 2023 - mdpi.com
For many years, we have faced the complications of viral hepatitis and alcohol-related liver
diseases such as cirrhosis, decompensation, portal hypertension, and hepatocellular …

[HTML][HTML] The latest global burden of liver cancer: A past and present threat

JH Oh, DW Jun - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Liver cancer is the fourth most common cause of death globally, accounting for over 800,000
deaths annually. 1, 2 Hepatocellular carcinoma represents approximately 90% of primary …

Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease

HS Chun, M Lee, JS Lee, HW Lee, BK Kim… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Cardiovascular disease (CVD) is the main cause of mortality
in subjects with non‐alcoholic fatty liver disease (NAFLD). We investigated the association …

A review of MASLD-related hepatocellular carcinoma: progress in pathogenesis, early detection, and therapeutic interventions

Y Ma, J Wang, W Xiao, X Fan - Frontiers in Medicine, 2024 - frontiersin.org
The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) is
continuously rising, evolving into a global health challenge. Concurrently, cases of …

Multiomics profiling of buffy coat and plasma unveils etiology-specific signatures in hepatocellular carcinoma

J Hong, JW Eun, GO Baek, JY Cheong, S Park… - Clinical and Molecular …, 2024 - e-cmh.org
Methods We generated whole-transcriptome sequencing (WTS) and targeted proteome data
from buffy coat and plasma samples from HCC patients. By integrating etiological …

[HTML][HTML] Mapping the Hidden Terrain of Hepatocellular Carcinoma: Exploring Regional Differences in Incidence and Mortality across Two Decades by Using the …

Y Abboud, VP Shah, M Bebawy, A Al-Khazraji… - Journal of Clinical …, 2024 - mdpi.com
Background: There is an observed variation in the burden of hepatocellular carcinoma
(HCC) across different US populations. Our study aims to comprehensively assess …

A multicenter propensity score analysis of significance of hepatic resection type for early-stage hepatocellular carcinoma

SC Tang, KL Zhang, KY Lin, YD Tang, J Fu… - Hepatology …, 2024 - Springer
Background The impact of hepatic resection type on long-term oncological prognosis of
patients with early-stage hepatocellular carcinoma (HCC) has not been systematically …

[HTML][HTML] Association of physical activity, including amount and maintenance, with the risk of HCC among patients with type 2 diabetes

W Han, K Han, SG Hwang, SH Ahn, MN Kim - JHEP Reports, 2024 - Elsevier
Background & Aims We investigated the association of physical activity (PA) levels and
changes with the risk of hepatocellular carcinoma (HCC) in patients with type 2 diabetes …

[HTML][HTML] Hepatocellular carcinoma surveillance in non-alcoholic fatty liver disease–who and how?

MLP Teng, DJH Tan, CH Ng… - Clinical and Molecular …, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is the fastestgrowing cause of hepatocellular
carcinoma (HCC) globally. 1 The burden of NAFLD-related HCC is predicted to increase …

MASLD-Related HCC: A Comprehensive Review of the Trends, Pathophysiology, Tumor Microenvironment, Surveillance, and Treatment Options

Y Shi, E Taherifard, A Saeed, A Saeed - Current Issues in Molecular …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) represents a significant burden on global healthcare
systems due to its considerable incidence and mortality rates. Recent trends indicate an …