Estrogens induce tumors in laboratory animals and have been associated with breast and
uterine cancers in humans. In relation to the role of estrogens in the induction of cancer, we …

Exposure to estrogens is associated with increased risk of breast and other types of human
cancer. Estrogens are converted to metabolites, particularly the catechol estrogen-3, 4 …

Expression of nuclear factor-kappaB (NF-kappaB)/Rel transcription factors has recently
been found to promote cell survival, inhibiting the induction of apoptosis. In most cells other …

Certain protease inhibitors, called the anticarcinogenic protease inhibitors in this review, are
capable of preventing carcinogenesis in a wide variety of in vivo and in vitro model systems …

Animal experiments and in vitro studies have shown that compounds found in tobacco
smoke, such as polycyclic hydrocarbons, aromatic amines, and N-nitrosamines, may induce …

NF-κB/Rel transcription factors regulate many genes involved in control of cellular
proliferation, neoplastic transformation, and apoptosis, including the c-myc oncogene …

Breast cancer, which is the most common neoplastic disease in females and accounts for up
to one third of all new cases of women's cancer in North America, continues to rise in …

The endogenous ligand-activated aryl hydrocarbon receptor (AHR) plays an important role
in numerous biologic processes. As the known number of AHR-mediated processes grows …

Estrogens play a crucial role in the development and evolution of human breast cancer.
However, it is still unclear whether estrogens are carcinogenic to the human breast. There …

Epidemiological evidence suggests tea (Camellia sinensis L.) has chemopreventive effects
against various tumors. Green tea contains many polyphenols, including epigallocatechin‐3 …