The vermiform appendix is the primary site of several distinctive benign and malignant
neoplasms. Some can produce the clinical syndrome of pseudomyxoma peritonei (PMP). A …

Abstract High-throughput “-omics” analysis may provide a broader and deeper
understanding of cancer biology to define prognostic and predictive biomarkers and identify …

Invasive mucinous adenocarcinoma (IMA) of the lung is a unique variant of lung
adenocarcinoma. Aberrant mucin expression is associated with cancer development and …

Background Appendiceal adenocarcinoma (AA) is an orphan disease with unique clinical
attributes but often treated as colorectal cancer (CRC). Understanding key molecular …

Goblet cell carcinoid (GCC) is a rare appendiceal tumor with unique morphologic features
that shows glandular and neuroendocrine differentiation on immunohistochemistry. An …

Introduction Invasive mucinous lung adenocarcinoma (IMA) has unique radiological findings
and pathological characteristics. IMA is classified into solitary and pneumonic types; …

Context.—High-grade appendiceal mucinous neoplasm (HAMN) is a relatively recently
introduced term describing a rare epithelial neoplasm of the appendix that demonstrates …

GNAS mutations have been described in mucinous and non-mucinous epithelial neoplasms
of the appendix, pancreas, and colon, with hotspot GNAS mutations found in up to two-thirds …

Given the management options now available, accurate diagnosis of the neoplasms
discussed in this article is increasingly important. Many are unusual, and histologic …

Appendiceal mucinous tumors (AMTs) include low-grade mucinous appendiceal neoplasms
(LAMNs), high-grade mucinous appendiceal neoplasms (HAMNs), and mucinous …