Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …
Nigella sativa in controlling Type 2 diabetes, cardiovascular, and rheumatoid arthritis diseases: Molecular aspects
V Hadi, N Pahlavani, M Malekahmadi… - Journal of Research …, 2021 - journals.lww.com
Oxidative stress is an important factor in the etiology of several chronic diseases that include
cardiovascular disease (CVD), Type 2 diabetes (T2D), and rheumatoid arthritis (RA) …
cardiovascular disease (CVD), Type 2 diabetes (T2D), and rheumatoid arthritis (RA) …
Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies
Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …
Nigella sativa L. and Its Active Compound Thymoquinone in the Clinical Management of Diabetes: A Systematic Review
MF Mahomoodally, MZ Aumeeruddy… - International journal of …, 2022 - mdpi.com
Despite existing conventional hypoglycemic drugs to manage diabetes, their non-availability
and cost in low-income countries coupled with the associated side effects remain a major …
and cost in low-income countries coupled with the associated side effects remain a major …
Development and characterization of a fucoidan-based nanoemulsion using Nigella sativa oil for improvement of anti-obesity activity of fucoxanthin in an obese rat …
The anti-obesity activity of encapsulated fucoxanthin in fucoidan-based nanoemulsion was
investigated. Then, high-fat diet (HFD) induced-obese rats were fed along with different …
investigated. Then, high-fat diet (HFD) induced-obese rats were fed along with different …
Natural product heme oxygenase inducers as treatment for nonalcoholic fatty liver disease
DE Stec, TD Hinds Jr - International Journal of Molecular Sciences, 2020 - mdpi.com
Heme oxygenase (HO) is a critical component of the defense mechanism to a wide variety of
cellular stressors. HO induction affords cellular protection through the breakdown of toxic …
cellular stressors. HO induction affords cellular protection through the breakdown of toxic …
The effect of Nigella sativa (black seed) on biomarkers of inflammation and oxidative stress: an updated systematic review and meta-analysis of randomized …
Objective This study was conducted to assess the effect of Nigella sativa (N. sativa)
supplementation on inflammatory and oxidative markers among the adult population …
supplementation on inflammatory and oxidative markers among the adult population …
Black Cumin Seed (Nigella sativa) in Inflammatory Disorders: Therapeutic Potential and Promising Molecular Mechanisms
HK Rashwan, S Mahgoub, NZ Abuelezz… - Drugs and Drug …, 2023 - mdpi.com
Inflammation is an essential defense mechanism against harmful stimuli. However,
uncontrolled inflammatory mechanisms culminate in disturbed responses that contribute to …
uncontrolled inflammatory mechanisms culminate in disturbed responses that contribute to …
Potential Pharmacological Applications of Nigella Seeds with a Focus on Nigella sativa and Its Constituents against Chronic Inflammatory Diseases: Progress and …
S Wahab, A Alsayari - Plants, 2023 - mdpi.com
The leading cause of death worldwide has been identified as chronic illnesses, according to
the World Health Organization (WHO). Chronic inflammatory conditions such as asthma …
the World Health Organization (WHO). Chronic inflammatory conditions such as asthma …
Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …
Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …
macrophages. It is known as a'double-edged sword'because it is responsible for …