Effect of physical activity/exercise on oxidative stress and inflammation in muscle and vascular aging

M El Assar, A Álvarez-Bustos, P Sosa, J Angulo… - International Journal of …, 2022 - mdpi.com
Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

[HTML][HTML] Sarcopenic obesity: emerging mechanisms and therapeutic potential

CL Axelrod, WS Dantas, JP Kirwan - Metabolism, 2023 - Elsevier
Sarcopenic obesity, or the loss of muscle mass and function associated with excess
adiposity, is a largely untreatable medical condition associated with diminished quality of life …

Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy

S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …

The mechanisms and treatments for sarcopenia: could exosomes be a perspective research strategy in the future?

S Rong, L Wang, Z Peng, Y Liao, D Li… - Journal of cachexia …, 2020 - Wiley Online Library
The age‐related loss of muscle mass and muscle function known as sarcopenia is a primary
contributor to the problems faced by the old people. Sarcopenia has been a major public …

Inflammatory signatures in older persons with physical frailty and sarcopenia: The frailty “cytokinome” at its core

E Marzetti, A Picca, F Marini, A Biancolillo… - Experimental …, 2019 - Elsevier
Background The construct of physical frailty and sarcopenia (PF&S) identifies an age-related
pre-disability condition defined by reduced physical performance and low muscle mass …

Organokines, sarcopenia, and metabolic repercussions: the vicious cycle and the interplay with exercise

G Minniti, LM Pescinini-Salzedas, GAS Minniti… - International journal of …, 2022 - mdpi.com
Sarcopenia is a disease that becomes more prevalent as the population ages, since it is
directly linked to the process of senility, which courses with muscle atrophy and loss of …

Cellular and molecular mechanisms of sarcopenia: the S100B perspective

F Riuzzi, G Sorci, C Arcuri, I Giambanco… - Journal of cachexia …, 2018 - Wiley Online Library
Primary sarcopenia is a condition of reduced skeletal muscle mass and strength, reduced
agility, and increased fatigability and risk of bone fractures characteristic of aged, otherwise …

Isoquercitrin delays denervated soleus muscle atrophy by inhibiting oxidative stress and inflammation

Y Shen, Q Zhang, Z Huang, J Zhu, J Qiu, W Ma… - Frontiers in …, 2020 - frontiersin.org
Although denervated muscle atrophy is common, the underlying molecular mechanism
remains unelucidated. We have previously found that oxidative stress and inflammatory …

Understanding the consequences of fatty bone and fatty muscle: how the osteosarcopenic adiposity phenotype uncovers the deterioration of body composition

K Hu, E Deya Edelen, W Zhuo, A Khan, J Orbegoso… - Metabolites, 2023 - mdpi.com
Adiposity is central to aging and several chronic diseases. Adiposity encompasses not just
the excess adipose tissue but also body fat redistribution, fat infiltration, hypertrophy of …

Involvement of phosphatidylserine receptors in the skeletal muscle regeneration: therapeutic implications

Z Szondy, N Al‐Zaeed, N Tarban, É Fige… - Journal of Cachexia …, 2022 - Wiley Online Library
Sarcopenia is a progressive loss of muscle mass and strength with a risk of adverse
outcomes such as disability, poor quality of life, and death. Increasing evidence indicates …