Adverse effects of amorphous silica nanoparticles: focus on human cardiovascular health

C Guo, Y Liu, Y Li - Journal of Hazardous Materials, 2021 - Elsevier
Amorphous silica nanoparticle (SiNPs) has tremendous potential for a host of applications,
while its mass production, broad application and environmental release inevitably increase …

[HTML][HTML] Engineered silica nanomaterials in pesticide delivery: challenges and perspectives

J Zhang, S Kothalawala, C Yu - Environmental Pollution, 2023 - Elsevier
Over the past decade, nanopesticide has been developed rapidly for exploring effective and
safe alternatives to conventional pesticides with significant drawbacks and risks. Many …

In-vitro in-vivo correlation (IVIVC) in nanomedicine: Is protein corona the missing link?

P Jain, RS Pawar, RS Pandey, J Madan, S Pawar… - Biotechnology …, 2017 - Elsevier
One of the unmet challenges in nanotechnology is to understand and establish the
relationship between physicochemical properties of nanoparticles (NPs) and its biological …

Bacteria under stress by complement and coagulation

ETM Berends, A Kuipers, MM Ravesloot… - FEMS microbiology …, 2014 - academic.oup.com
The complement and coagulation systems are two related protein cascades in plasma that
serve important roles in host defense and hemostasis, respectively. Complement activation …

Advances and future perspectives of intranasal drug delivery: A scientometric review

D Xu, XJ Song, X Chen, JW Wang, YL Cui - Journal of Controlled Release, 2024 - Elsevier
Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

Silica nanoparticles in transmucosal drug delivery

TM M. Ways, KW Ng, WM Lau, VV Khutoryanskiy - Pharmaceutics, 2020 - mdpi.com
Transmucosal drug delivery includes the administration of drugs via various mucous
membranes, such as gastrointestinal, nasal, ocular, and vaginal mucosa. The use of …

Action of nanoparticles on platelet activation and plasmatic coagulation

E Fröhlich - Current medicinal chemistry, 2016 - ingentaconnect.com
Nanomaterials can get into the blood circulation after injection or by release from implants
but also by permeation of the epithelium after oral, respiratory or dermal exposure. Once in …

Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Y Yang, X Du, Q Wang, J Liu… - International …, 2019 - spandidos-publications.com
Silicon is one of the most widely used chemical materials, and the increasing use of silica
nanoparticles (SNs) highlights the requirement for safety and biological toxicity studies. The …

Long-term respiratory exposure to amorphous silica nanoparticles promoted systemic inflammation and progression of fibrosis in a susceptible mouse model

X Li, Y Li, S Lv, H Xu, R Ma, Z Sun, Y Li, C Guo - Chemosphere, 2022 - Elsevier
Exposure to amorphous silica nanoparticles (SiNPs) has increased dramatically, and
concerns are growing about their potential health effects. However, their long-term systemic …

Adverse effects and underlying mechanism of amorphous silica nanoparticles in liver

Q Liang, M Sun, Y Ma, F Wang, Z Sun, J Duan - Chemosphere, 2023 - Elsevier
Amorphous silica nanoparticles (SiNPs) have been widely used and mass-producted due to
its unique properties. With the life cycle of SiNPs-based products, SiNPs are further released …