IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

Abstract Interleukin-6 (IL-6) is a multifunctional cytokine with well-defined pro-and anti-
inflammatory properties. Although only small amounts in the picogram range can be …

Metabolic syndrome (MS) is a collection of cardiometabolic risk factors that includes obesity,
insulin resistance, hypertension, and dyslipidemia. Although there has been significant …

Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

The pleiotropic cytokine interleukin-6 (IL-6) is involved in numerous physiological and
pathophysiological functions that include development, immune cell differentiation …

Immunoglobulin-A vasculitis (IgAV) is classically a childhood small-sized blood vessel
vasculitis with predominant involvement of the skin. Gastrointestinal and joint manifestations …

Interleukin-6 (IL-6) is a multifunctional pro-inflammatory cytokine that is tightly regulated and
expressed at low levels in healthy individuals. Increased IL-6 expression has been …

Inflammation plays a major role in the onset of cardiovascular disease (CVD). Interleukine‐6
(IL‐6) is a multifunctional cytokine involved both in the beneficial acute inflammatory …

Obesity is linked with many deleterious health consequences and is associated with
increased risk of chronic disease including type 2 diabetes, atherosclerosis and certain …

Human herpesvirus 8 encodes a viral version of interleukin-6 (vIL-6) which shows 25%
sequence homology with human IL-6. In contrast to human IL-6, which first binds to the IL-6 …