[HTML][HTML] Obesogens: How they are identified and molecular mechanisms underlying their action
N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
[HTML][HTML] Reduced birth weight and exposure to per-and polyfluoroalkyl substances: A review of possible underlying mechanisms using the AOP-HelpFinder
C Gundacker, K Audouze, R Widhalm, S Granitzer… - Toxics, 2022 - mdpi.com
Prenatal exposure to per-and polyfluorinated substances (PFAS) may impair fetal growth.
Our knowledge of the underlying mechanisms is incomplete. We used the Adverse Outcome …
Our knowledge of the underlying mechanisms is incomplete. We used the Adverse Outcome …
Hexafluoropropylene oxide trimer acid (HFPO-TA) disturbs embryonic liver and biliary system development in zebrafish
S Sun, X Li, L Zhang, Z Zhong, C Chen, Y Zuo… - Science of The Total …, 2023 - Elsevier
Hexafluoropropylene oxide trimer acid (HFPO-TA), a novel alternative to perfluorooctanoic
acid (PFOA), has emerged as a potential environmental pollutant. Here, to investigate the …
acid (PFOA), has emerged as a potential environmental pollutant. Here, to investigate the …
Associations of gestational perfluoroalkyl substances exposure with early childhood BMI z-scores and risk of overweight/obesity: results from the ECHO cohorts
Y Liu, AC Wosu, AF Fleisch, AL Dunlop… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Gestational per-and polyfluoroalkyl substances (PFAS) exposure may be
associated with adiposity and increased risk of obesity among children and adolescents …
associated with adiposity and increased risk of obesity among children and adolescents …
Hexafluoropropylene oxide trimer acid exposure triggers necroptosis and inflammation through the Wnt/β-catenin/NF-κB axis in the liver
X Zhang, B Li, S Huo, J Du, J Zhang, M Song… - Science of The Total …, 2023 - Elsevier
Hexafluoropropylene oxide trimer acid (HFPO-TA), an emerging alternative to
perfluorooctanoic acid (PFOA), has recently been identified as a significant environmental …
perfluorooctanoic acid (PFOA), has recently been identified as a significant environmental …
[HTML][HTML] The effects of combined exposure to bisphenols and perfluoroalkyls on human perinatal stem cells and the potential Implications for health outcomes
A Di Credico, G Gaggi, I Bucci, B Ghinassi… - International Journal of …, 2023 - mdpi.com
The present study investigates the impact of two endocrine disruptors, namely Bisphenols
(BPs) and Perfluoroalkyls (PFs), on human stem cells. These chemicals leach from plastic …
(BPs) and Perfluoroalkyls (PFs), on human stem cells. These chemicals leach from plastic …
[HTML][HTML] Exposure to perfluoroalkyl and polyfluoroalkyl substances and pediatric obesity: a systematic review and meta-analysis
B Frangione, S Birk, T Benzouak… - International Journal of …, 2024 - nature.com
Introduction Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are potentially
obesogenic for children. We undertook a systematic review to synthesize this literature and …
obesogenic for children. We undertook a systematic review to synthesize this literature and …
Maternal PFOS exposure in mice induces hepatic lipid accumulation and inflammation in adult female offspring: Involvement of microbiome-gut-liver axis and …
W Yi, J Shi, L Wang, D Wang, Y Wang, J Song… - Journal of Hazardous …, 2024 - Elsevier
Perfluorooctane sulfonates (PFOS) are the persistent organic pollutants. In the present
study, 0, 0.3, or 3-mg/kg PFOS were administered to pregnant mice from GD 11 to GD 18 …
study, 0, 0.3, or 3-mg/kg PFOS were administered to pregnant mice from GD 11 to GD 18 …
[HTML][HTML] Prenatal and childhood exposure to per-/polyfluoroalkyl substances (PFASs) and its associations with childhood overweight and/or obesity: a systematic …
G Frigerio, CM Ferrari, S Fustinoni - Environmental Health, 2023 - Springer
Abstract Background Per-/polyfluoroalkyl substances (PFASs) are persistent organic
pollutants and suspected endocrine disruptors. Objective The aim of this work was to …
pollutants and suspected endocrine disruptors. Objective The aim of this work was to …
Hexafluoropropylene oxide trimer acid, a perfluorooctanoic acid alternative, induces cardiovascular toxicity in zebrafish embryos
S Sun, L Zhang, X Li, L Zang, L Huang, J Zeng… - Journal of …, 2024 - Elsevier
As an increasingly used alternative to perfluorooctanoic acid (PFOA), hexafluoropropylene
oxide trimer acid (HFPO-TA) has been widely detected in global water environments …
oxide trimer acid (HFPO-TA) has been widely detected in global water environments …