Serotonin in affective control
P Dayan, QJM Huys - Annual review of neuroscience, 2009 - annualreviews.org
Serotonin is a neuromodulator that is extensively entangled in fundamental aspects of brain
function and behavior. We present a computational view of its involvement in the control of …
function and behavior. We present a computational view of its involvement in the control of …
An integrative review on role and mechanisms of ghrelin in stress, anxiety and depression
A Bali, A Singh Jaggi - Current drug targets, 2016 - ingentaconnect.com
Ghrelin is orexigenic hormone primarily synthesized by endocrine X/A-like cells of gastric
oxyntic mucosa to stimulate appetite and food intake along with regulation of growth …
oxyntic mucosa to stimulate appetite and food intake along with regulation of growth …
Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats
BACKGROUND: Vagal nerve stimulation (VNS) is used for treatment-refractory depression,
but there are few preclinical studies of its effects when administered repeatedly over time …
but there are few preclinical studies of its effects when administered repeatedly over time …
Constitutive increases in amygdalar corticotropin-releasing factor and fatty acid amide hydrolase drive an anxious phenotype
Background Corticotropin-releasing factor (CRF) mediates anxiogenic responses by
activating CRF type 1 (CRF 1) receptors in limbic brain regions. Anxiety is further modulated …
activating CRF type 1 (CRF 1) receptors in limbic brain regions. Anxiety is further modulated …
The crosstalk between brain mediators regulating food intake behavior in birds: a review
Appetite is controlled by a complex system of central and peripheral signals interacting to
modulate the ingestion response. Several brain mediators with complex networks adjust …
modulate the ingestion response. Several brain mediators with complex networks adjust …
Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats
GV Carr, LE Schechter, I Lucki - Psychopharmacology, 2011 - Springer
Rationale Although selective serotonin reuptake inhibitors (SSRIs) produce clinical
therapeutic effects on depression and anxiety through augmentation of serotonergic …
therapeutic effects on depression and anxiety through augmentation of serotonergic …
Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences
The vesicular monoamine transporter type 2 gene (VMAT2) has a crucial role in the storage
and synaptic release of all monoamines, including serotonin (5-HT). To evaluate the specific …
and synaptic release of all monoamines, including serotonin (5-HT). To evaluate the specific …
Tryptophan hydroxylase 2 as a therapeutic target for psychiatric disorders: Focus on animal models
EA Kulikova, AV Kulikov - Expert Opinion on Therapeutic Targets, 2019 - Taylor & Francis
ABSTRACT Introduction: Tryptophan hydroxylase 2 (TPH2) is the key, rate-limiting enzyme
of serotonin (5-HT) synthesis in the brain. Some polymorphic variants of the human Tph2 …
of serotonin (5-HT) synthesis in the brain. Some polymorphic variants of the human Tph2 …
Tryptophan as an evolutionarily conserved signal to brain serotonin: molecular evidence and psychiatric implications
S Russo, IP Kema, F Bosker, J Haavik… - The world journal of …, 2009 - Taylor & Francis
The role of serotonin (5-HT) in psychopathology has been investigated for decades. Among
others, symptoms of depression, panic, aggression and suicidality have been associated …
others, symptoms of depression, panic, aggression and suicidality have been associated …
Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior
JR Turner, LM Castellano, JA Blendy - Journal of Pharmacology and …, 2010 - ASPET
Clinical and preclinical studies suggest that nicotinic acetylcholine receptors are involved in
affective disorders; therefore, the potential therapeutic value of nicotinic partial agonists as …
affective disorders; therefore, the potential therapeutic value of nicotinic partial agonists as …