[HTML][HTML] Extracellular matrix components and mechanosensing pathways in health and disease

A Berdiaki, M Neagu, P Tzanakakis, I Spyridaki… - Biomolecules, 2024 - mdpi.com
Glycosaminoglycans (GAGs) and proteoglycans (PGs) are essential components of the
extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways. GAGs …

Phototuning of Hyaluronic‐Acid‐Based Hydrogel Properties to Control Network Formation in Human Vascular Endothelial Cells

KCML Elvitigala, L Mohan, W Mubarok… - Advanced Healthcare …, 2024 - Wiley Online Library
In vitro network formation by endothelial cells serves as a fundamental model for studies
aimed at understanding angiogenesis. The morphogenesis of these cells to form a network …

Multi-parameter tunable synthetic matrix for engineering lymphatic vessels

L Alderfer, S Saha, F Fan, J Wu, LE Littlepage… - Communications …, 2024 - nature.com
Controlling the formation of new lymphatic vessels has been postulated as an innovative
therapeutic strategy for various disease phenotypes, including neurodegenerative diseases …

Seeing and Cleaving: Turn-Off Fluorophore Uncaging and Its Application in Hydrogel Photopatterning and Traceable Neurotransmitter Photocages

O Pantl, B Chiovini, G Szalay, G Turczel… - … Applied Materials & …, 2024 - ACS Publications
The advancements in targeted drug release and experimental neuroscience have amplified
the scientific interest in photolabile protecting groups (PPGs) and photouncaging. The …

[HTML][HTML] Temperature-Regulated Synthesis of Hyaluronic Acid-Interpenetrated Polyacrylamide/Poly (Acrylic Acid Sodium Salt) Semi-Interpenetrated Polymer Network …

N Özcan, N Orakdogen - Gels, 2024 - mdpi.com
An alternative synthetic pathway was proposed for the optimization of synthesis to find a
better correlation between the swelling and elasticity of hyaluronic acid-interpenetrated gels …

Application of Nanomaterials in the Repair and Regeneration of Lymphatic Organs and Corresponding Biophysical Simulation Strategies

B Liu, DA Wang - Advanced NanoBiomed Research, 2024 - Wiley Online Library
Immune system diseases, malignant tumors, and traumatic injuries can directly damage the
structure and function of lymphoid organs, while subsequent radiotherapy, chemotherapy …

[HTML][HTML] Robust Differentiation of Human Pluripotent Stem Cells into Lymphatic Endothelial Cells Using Transcription Factors

S Saha, F Graham, J Knopp, C Patzke… - Cells Tissues …, 2024 - karger.com
Introduction: Generating new lymphatic vessels has been postulated as an innovative
therapeutic strategy for various disease phenotypes, including neurodegenerative diseases …

中枢神经系统边界相关巨噬细胞在大脑稳态和脑疾病中作用的研究进展

邵晨硕, 韦立航, 谭国鹤 - 解剖学报, 2024 - jpxb.bjmu.edu.cn
随着中枢神经系统“免疫豁免” 的观点被打破, 越来越多的研究聚焦于免疫调节在中枢神经系统
疾病中的重要作用. 其中, 中枢神经系统边界相关巨噬细胞(BAMs) 在大脑稳态和脑疾病调节中的 …

Intracellular pH dynamics respond to microenvironment stiffening and mediate vasculogenic mimicry through β-catenin

LM Lund, AN Marchi, L Alderfer, E Hall, J Hammer… - …, 2024 - pmc.ncbi.nlm.nih.gov
Dysregulated intracellular pH (pHi) dynamics and an altered tumor microenvironment have
emerged as drivers of cancer cell phenotypes. However, the molecular integration between …

[HTML][HTML] Characterization of Photo-Crosslinked Methacrylated Type I Collagen as a Platform to Investigate the Lymphatic Endothelial Cell Response

BNK Ruliffson, SM Larson, EK Xhupi, DL Herrera-Diaz… - Lymphatics, 2024 - mdpi.com
Despite chronic fibrosis occurring in many pathological conditions, few in vitro studies
examine how fibrosis impacts lymphatic endothelial cell (LEC) behavior. This study …