ADAM10 (A Disintegrin and Metalloproteinase 10) has been identified as the major
physiological alpha-secretase in neurons, responsible for cleaving APP in a non …

Abstract Background The lncRNA LINC00460 plays crucial roles in several epithelial
cancers, although its mechanisms of action differ greatly in different cellular contexts. In this …

MicroRNAs (miRNAs) belong to a group of short RNA molecules of~ 22 nucleotides that play
a significant role in the regulation of gene expression through post-transcriptional regulatory …

Exosomes derived from human umbilical cord mesenchymal stem cells (hucMSCs)
expressing microRNAs (miRNAs) have been highlighted in human cancers. However, the …

Background Head and neck cancer (HNC) is one of the most common deadly diseases
worldwide. An increasing number of studies have recently focused on the malignant …

The matrix-specific protein periostin (POSTN) is up-regulated in human cancers and
associated with cancer growth, metastasis and angiogenesis. Although the stroma of cancer …

Emerging evidence indicates that lncRNAs play important roles in cancer tumourigenesis
and could be used as potential diagnostic biomarkers or therapeutic targets. However, the …

Cancer stem cells (CSCs) are key cellular targets for effective cancer therapy, due to their
critical roles in cancer progression and chemo/radio-resistance. Emerging evidence …

Prostate cancer and benign prostate hyperplasia (BPH) are heterogeneous disorders with a
wide array of clinical presentations and high prevalence among men. Several protein coding …

Accumulating evidences indicate that non-coding RNAs play crucial roles in the progression
of an extensive range of carcinomas. This study aimed to investigate the action mechanism …