Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
Zebrafish as an emerging model for studying complex brain disorders
AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …
Zebrafish models for translational neuroscience research: from tank to bedside
The zebrafish (Danio rerio) is emerging as a new important species for studying
mechanisms of brain function and dysfunction. Focusing on selected central nervous system …
mechanisms of brain function and dysfunction. Focusing on selected central nervous system …
Prevalence of autism spectrum disorder phenomenology in genetic disorders: a systematic review and meta-analysis
C Richards, C Jones, L Groves, J Moss… - The Lancet …, 2015 - thelancet.com
Background Autism spectrum disorder (ASD) phenomenology is reported to be more
common in individuals with some genetic syndromes than in the general population; …
common in individuals with some genetic syndromes than in the general population; …
Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials
E Berry-Kravis, V Des Portes, R Hagerman… - Science translational …, 2016 - science.org
Fragile X syndrome (FXS), the most common cause of inherited intellectual disability and
autistic spectrum disorder, is typically caused by transcriptional silencing of the X-linked …
autistic spectrum disorder, is typically caused by transcriptional silencing of the X-linked …
[HTML][HTML] Autism spectrum disorders and neuropathology of the cerebellum
DR Hampson, GJ Blatt - Frontiers in neuroscience, 2015 - frontiersin.org
The cerebellum contains the largest number of neurons and synapses of any structure in the
central nervous system. The concept that the cerebellum is solely involved in fine motor …
central nervous system. The concept that the cerebellum is solely involved in fine motor …
Comorbidity of intellectual disability confounds ascertainment of autism: implications for genetic diagnosis
While recent studies suggest a converging role for genetic factors towards risk for
nosologically distinct disorders including autism, intellectual disability (ID), and epilepsy …
nosologically distinct disorders including autism, intellectual disability (ID), and epilepsy …
Candidate biomarkers in children with autism spectrum disorder: a review of MRI studies
D Li, HO Karnath, X Xu - Neuroscience bulletin, 2017 - Springer
Searching for effective biomarkers is one of the most challenging tasks in the research field
of Autism Spectrum Disorder (ASD). Magnetic resonance imaging (MRI) provides a non …
of Autism Spectrum Disorder (ASD). Magnetic resonance imaging (MRI) provides a non …
Biomarkers in autism spectrum disorder: the old and the new
B Ruggeri, U Sarkans, G Schumann, AM Persico - Psychopharmacology, 2014 - Springer
Rationale Autism spectrum disorder (ASD) is a complex heterogeneous
neurodevelopmental disorder with onset during early childhood and typically a life-long …
neurodevelopmental disorder with onset during early childhood and typically a life-long …
[HTML][HTML] Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic …
G Deidda, IF Bozarth, L Cancedda - Frontiers in cellular neuroscience, 2014 - frontiersin.org
During mammalian ontogenesis, the neurotransmitter GABA is a fundamental regulator of
neuronal networks. In neuronal development, GABAergic signaling regulates neural …
neuronal networks. In neuronal development, GABAergic signaling regulates neural …