[HTML][HTML] Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment

JW Clancy, C D'Souza-Schorey - Annual Review of Pathology …, 2023 - annualreviews.org
Tumor cells release extracellular vesicles (EVs) that can function as mediators of
intercellular communication in the tumor microenvironment. EVs contain a host of bioactive …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

[HTML][HTML] Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma

VM Ravi, P Will, J Kueckelhaus, N Sun, K Joseph… - Cancer cell, 2022 - cell.com
Glioblastomas are malignant tumors of the central nervous system hallmarked by subclonal
diversity and dynamic adaptation amid developmental hierarchies. The source of dynamic …

Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry

H Liu, Y Tian, C Xue, Q Niu, C Chen… - Journal of extracellular …, 2022 - Wiley Online Library
It has been demonstrated recently that extracellular vesicles (EVs) carry DNA; however,
many fundamental features of DNA in EVs (EV‐DNA) remain elusive. In this study, a …

Single extracellular VEsicle nanoscopy

A Saftics, S Abuelreich, E Romano… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) and their cargo constitute novel biomarkers. EV subpopulations
have been defined not only by abundant tetraspanins (eg, CD9, CD63 and CD81) but also …

Liquid biopsy in gliomas: A RANO review and proposals for clinical applications

R Soffietti, C Bettegowda, IK Mellinghoff… - Neuro …, 2022 - academic.oup.com
Background There is an extensive literature highlighting the utility of blood-based liquid
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

[HTML][HTML] MGMT and whole-genome DNA methylation impacts on diagnosis, prognosis and therapy of glioblastoma multiforme

R Della Monica, M Cuomo, M Buonaiuto… - International Journal of …, 2022 - mdpi.com
Epigenetic changes in DNA methylation contribute to the development of many diseases,
including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and …

A framework for efficient brain tumor classification using MRI images

Y Guan, M Aamir, Z Rahman, A Ali, WA Abro, ZA Dayo… - 2021 - ntnuopen.ntnu.no
A brain tumor is an abnormal growth of brain cells inside the head, which reduces the
patient's survival chance if it is not diagnosed at an earlier stage. Brain tumors vary in size …