The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …

A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …

The delivery of probiotics to the microbiota is a promising method to prevent and treat
diseases. However, oral probiotics will suffer from gastrointestinal insults, especially the …

As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Reactive oxygen species (ROS)-sensitive drug delivery systems (DDS) specifically
responding to altered levels of ROS in the pathological microenvironment have emerged as …

An oral nanoparticle (NPs) encapsulated in chitosan/alginate hydrogel (CA-Gel) with dual-
sensitive in pH and reactive oxygen species (ROS) was developed to load curcumin (CUR) …

The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

Reactive oxygen species (ROS) are essential in regulating various physiological functions.
However, overproduction of ROS is implicated in the pathogenesis of various inflammatory …