Automated methods for protein structure determination by NMR have increasingly gained
acceptance and are now widely used for the automated assignment of distance restraints …

Around half of all protein structures solved nowadays using solution-state nuclear magnetic
resonance (NMR) spectroscopy have been because of automated data analysis. The …

This chapter gives an overview of automated protein structure determination by nuclear
magnetic resonance (NMR) with the UNIO protocol that enables high to full automation of all …

Denoising multidimensional NMR-spectra is a fundamental step in NMR protein structure
determination. The state-of-the-art method uses wavelet-denoising, which may suffer when …

Error tolerant backbone resonance assignment is the cornerstone of the NMR structure
determination process. Although a variety of assignment approaches have been developed …

We have developed a graphics based algorithm for semi-automated protein NMR
assignments. Using the basic sequential triple resonance assignment strategy, the method …

One bottleneck in NMR structure determination lies in the laborious and time-consuming
process of side-chain resonance and NOE assignments. Compared to the well-studied …

Although three-dimensional protein structure determination using nuclear magnetic
resonance (NMR) spectroscopy is a computationally costly and tedious process that would …

Sequential resonance assignment represents an essential step towards the investigation of
protein structure, dynamics, and interaction surfaces. Although the experimental sensitivity …

Over the last years, my research activity has mainly been focused on Distance Geometry
(DG). Differently from the classical Euclidean Geometry, DG solely relies on distances, and …