Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

Non-coding RNA (ncRNA) is a kind of RNA, produced by genomic transcription and does
not encode protein, but can regulate the function of genes, thus widely regulating …

Inflammation has been shown to play an important role in the mechanisms involved in the
pathogenesis of hypertension. Accordingly, innate and adaptive immune responses …

Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is
etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke …

Abstract CD4+ CD25+ regulatory T cells (Tregs) are a class of CD4+ T cells with
immunosuppressive functions that play a critical role in maintaining immune homeostasis …

This study aimed to investigate the role and underlying mechanism of exosomes secreted by
oxidized low-density lipoprotein (oxLDL)-stimulated macrophages in the progression of …

Background Decreased activity of the enzyme paraoxonase-1 (PON1) has been
demonstrated in cardiovascular diseases. Statins, the forefront of pharmacotherapy for …

Telomeres are specialized nucleoprotein structures located at the end of linear
chromosomes and telomerase is the enzyme responsible for telomere elongation …

Once considered as inert, the extracellular matrix recently revealed to be biologically active.
Elastin is one of the most important components of the extracellular matrix. Many vital organs …

Rationale: Thyroid hormones have been linked with various proatherogenic and
antiatherogenic processes. However, the relationship of thyroid function with manifestations …