Microfluidic nanoparticles for drug delivery
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …
Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Strategies, design, and chemistry in siRNA delivery systems
Emerging therapeutics that utilize RNA interference (RNAi) have the potential to treat broad
classes of diseases due to their ability to reversibly silence target genes. In August 2018, the …
classes of diseases due to their ability to reversibly silence target genes. In August 2018, the …
CD44-targeted nanocarrier for cancer therapy
Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …
Nanocarriers for cancer-targeted drug delivery
Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …
Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …
approaches that are used to both resist the nonspecific adhesion of proteins and improve …
Biodegradable synthetic polymers: Preparation, functionalization and biomedical application
Biodegradable polymers have been widely used and have greatly promoted the
development of biomedical fields because of their biocompatibility and biodegradability. The …
development of biomedical fields because of their biocompatibility and biodegradability. The …
Multifunctional polymeric micelles for delivery of drugs and siRNA
AM Jhaveri, VP Torchilin - Frontiers in pharmacology, 2014 - frontiersin.org
Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-
shell structure have been used as versatile carriers for delivery of drugs as well as nucleic …
shell structure have been used as versatile carriers for delivery of drugs as well as nucleic …
Knocking down barriers: advances in siRNA delivery
In the 10 years that have passed since the Nobel prize-winning discovery of RNA
interference (RNAi), billions of dollars have been invested in the therapeutic application of …
interference (RNAi), billions of dollars have been invested in the therapeutic application of …
[HTML][HTML] Current challenges of cancer anti-angiogenic therapy and the promise of nanotherapeutics
AME Abdalla, L Xiao, MW Ullah, M Yu, C Ouyang… - Theranostics, 2018 - ncbi.nlm.nih.gov
With growing interest in cancer therapeutics, anti-angiogenic therapy has received
considerable attention and is widely administered in several types of human cancers …
considerable attention and is widely administered in several types of human cancers …