[HTML][HTML] ERp57/PDIA3: new insight

S Chichiarelli, F Altieri, G Paglia, E Rubini… - Cellular & Molecular …, 2022 - Springer
The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …

[HTML][HTML] Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review

M Sohel, S Aktar, P Biswas, MA Amin… - Cancer …, 2023 - Wiley Online Library
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …

Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator

Z Jahanafrooz, N Motamed, B Rinner, A Mokhtarzadeh… - Life sciences, 2018 - Elsevier
Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

[HTML][HTML] Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …

Silibinin induces metabolic crisis in triple‐negative breast cancer cells by modulating EGFR‐MYC‐TXNIP axis: potential therapeutic implications

MA Iqbal, S Chattopadhyay, FA Siddiqui… - The FEBS …, 2021 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is an aggressive form of breast cancer with limited
treatment modalities and poor prognosis. Metabolic reprogramming in cancer is considered …

[HTML][HTML] Role of natural compounds in preventing and treating breast cancer

B Noel, SK Singh, JW Lillard Jr… - Frontiers in bioscience …, 2020 - ncbi.nlm.nih.gov
Breast cancer (BrCa) is the most commonly diagnosed cancer and the second leading
cause of cancer-related death in women. Alarming increases in the cases quests for more …

Silibinin sensitizes chemo-resistant breast cancer cells to chemotherapy

O Molavi, F Narimani, F Asiaee, S Sharifi… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Multiple drug resistance is the major obstacle to conventional chemotherapy.
Silibinin, a nontoxic naturally occurring compound, has anticancer activity and can increase …

[PDF][PDF] Silibinin in cancer therapy: A promising prospect

P Tiwari, K Mishra - Cancer Res Front, 2015 - researchgate.net
The potential anti-cancer properties of natural plant compounds have elicited widespread
interest in recent times since it is believed that they can substantially contribute to the …

[HTML][HTML] Silibinin triggers the mitochondrial pathway of apoptosis in human Oral squamous carcinoma cells

RM Iyengar, E Devaraj - Asian Pacific journal of cancer prevention …, 2020 - ncbi.nlm.nih.gov
Background: Silibinin, a natural polyphenolic flavonoid present in seed extracts of milk
thistle (Silybum marianum). It has been shown to interact with various cancer-related cell …