Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is clinically characterized by early-onset dementia, stroke …

The complexity of the blood–brain barrier (BBB) and neurovascular unit (NVU) was and still
is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the …

Background Cerebral small‐vessel disease (cSVD) is an important cause of stroke and
vascular dementia. Most cases are multifactorial, but an emerging minority have a …

Cerebral small vessel diseases (SVD) have been causally correlated with ischemic strokes,
leading to cognitive decline and vascular dementia. Neuroimaging and molecular genetic …

Background: Homozygous or compound heterozygous mutations in high temperature
requirement serine peptidase A1 (HTRA1) gene are responsible for cerebral autosomal …

Background Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is an extremely rare monogenic autosomal disease …

Background: Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is an autosomal recessive disorder characterized by …

Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL)(MIM 600142) is linked to homozygous mutations in the …

Aims Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is a life‐threatening, inherited, nonhypertensive arteriole …

Cerebral small vessel disease (SVD) is recognized to be the leading cause of vascular
dementia. Although the most cases are sporadic, familial monogenic causes have been …