[HTML][HTML] Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides
X Luo, H Chen, Y Song, Z Qin, L Xu, N He, Y Tan… - European Journal of …, 2023 - Elsevier
Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …
Various biomimetics, including peptides as antifungals
E Efremenko, A Aslanli, N Stepanov, O Senko… - Biomimetics, 2023 - mdpi.com
Biomimetics, which are similar to natural compounds that play an important role in the
metabolism, manifestation of functional activity and reproduction of various fungi, have a …
metabolism, manifestation of functional activity and reproduction of various fungi, have a …
AMPDeep: hemolytic activity prediction of antimicrobial peptides using transfer learning
Background Deep learning's automatic feature extraction has proven to give superior
performance in many sequence classification tasks. However, deep learning models …
performance in many sequence classification tasks. However, deep learning models …
Prediction of linear cationic antimicrobial peptides active against gram-negative and gram-positive bacteria based on machine learning models
Antimicrobial peptides (AMPs) are considered as promising alternatives to conventional
antibiotics in order to overcome the growing problems of antibiotic resistance …
antibiotics in order to overcome the growing problems of antibiotic resistance …
A framework for real-time monitoring, analysis and adaptive sampling of viral amplicon nanopore sequencing
R Munro, N Holmes, C Moore, M Carlile, A Payne… - Frontiers in …, 2023 - frontiersin.org
The ongoing SARS-CoV-2 pandemic demonstrates the utility of real-time sequence analysis
in monitoring and surveillance of pathogens. However, cost-effective sequencing requires …
in monitoring and surveillance of pathogens. However, cost-effective sequencing requires …
Deep mutational scanning and machine learning for the analysis of antimicrobial-peptide features driving membrane selectivity
Many antimicrobial peptides directly disrupt bacterial membranes yet can also damage
mammalian membranes. It is therefore central to their therapeutic use that rules governing …
mammalian membranes. It is therefore central to their therapeutic use that rules governing …
AMP-GSM: prediction of antimicrobial peptides via a grouping–scoring–modeling approach
Due to the increasing resistance of bacteria to antibiotics, scientists began seeking new
solutions against this problem. One of the most promising solutions in this field are …
solutions against this problem. One of the most promising solutions in this field are …
AMP-EBiLSTM: employing novel deep learning strategies for the accurate prediction of antimicrobial peptides
Y Wang, L Wang, C Li, Y Pei, X Liu, Y Tian - Frontiers in Genetics, 2023 - frontiersin.org
Antimicrobial peptides are present ubiquitously in intra-and extra-biological environments
and display considerable antibacterial and antifungal activities. Clinically, it has shown good …
and display considerable antibacterial and antifungal activities. Clinically, it has shown good …
Molecular research on oral diseases and related biomaterials: A journey from oral cell models to advanced regenerative perspectives
T Steinberg, MP Dieterle, P Tomakidi - International Journal of Molecular …, 2022 - mdpi.com
Oral diseases such as gingivitis, periodontitis, and oral cancer affect millions of people
worldwide. Much research has been conducted to understand the pathogenetic …
worldwide. Much research has been conducted to understand the pathogenetic …
Antimicrobial Peptides Prediction method based on sequence multidimensional feature embedding
B Dong, M Li, B Jiang, B Gao, D Li, T Zhang - Frontiers in Genetics, 2022 - frontiersin.org
Antimicrobial peptides (AMPs) are alkaline substances with efficient bactericidal activity
produced in living organisms. As the best substitute for antibiotics, they have been paid …
produced in living organisms. As the best substitute for antibiotics, they have been paid …