The cell, as the most fundamental unit of life, is a microcosm of biology in which the
confluence of nearly all aspects of classical physics (mechanics, statistical physics …

Studies of membrane proteins have revealed a direct link between the lipid environment and
the structure and function of some of these proteins. Although some of these effects involve …

Studying membrane proteins represents a major challenge in protein biochemistry, with one
of the major difficulties being the problems encountered when working outside the natural …

The lipid bilayer component of biological membranes is important for the distribution,
organization, and function of bilayer-spanning proteins. This regulation is due to both …

The simplest cell-like structure, the lipid bilayer vesicle, can respond to mechanical
deformation by elastic membrane dilation/thinning and curvature changes. When a protein is …

Mechanosensitive ion channels (MSCs) exist in all cells, but mechanosensitivity is a
phenotype not a genotype. Specialized mechanoreceptors such as the hair cells of the …

Membrane protein function is regulated by the host lipid bilayer composition. This regulation
may depend on specific chemical interactions between proteins and individual molecules in …

We used micropipette aspiration to directly measure the area compressibility modulus,
bending modulus, lysis tension, lysis strain, and area expansion of fluid phase 1-stearoyl, 2 …

The peptide GsMTx4, isolated from the venom of the tarantula Grammostola spatulata, is a
selective inhibitor of stretch-activated cation channels (SACs). The mechanism of inhibition …

Mechanosensitive ion channels are the primary transducers that convert mechanical force
into an electrical or chemical signal in hearing, touch, and other mechanical senses. Unlike …