Animal and human laboratory paradigms offer invaluable approaches to study the complex
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …

The incentive salience sensitization (ISS) theory of addiction holds that addictive behavior
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …

Background Little is known about event-level patterns of marijuana co-or tri-use with alcohol
and tobacco. Thus, the study goal was to examine patterns of same-day alcohol, cigarette …

Objective: Alcohol use disorder (AUD) remains an urgent public health problem.
Longitudinal data are needed to clarify the role of acute subjective responses to alcohol in …

Aims Alcohol use disorder is highly heterogeneous. One approach to understanding this
heterogeneity is the identification of drinker subtypes. A candidate classification consists of …

Naltrexone (NTX) has been widely studied for the treatment of alcohol use disorder with
overall support for its efficacy. The mechanisms of action of naltrexone are thought to involve …

Background/Objective: Determining the predictive variables associated with levels of alcohol
craving can ease the identification of patients who can benefit from treatments. This study …

Human alcohol laboratory studies use two routes of alcohol administration: ingestion and
infusion. The goal of this paper was to compare and contrast these alcohol administration …

Aim The purpose of this brief narrative review is to address the complexities and benefits of
extending animal alcohol addiction research to the human domain, emphasizing Allostasis …

Alcohol and substance use disorders are heterogeneous conditions with limited effective
treatment options. While there have been prior attempts to classify addiction subtypes, they …