Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery

A Ayati, S Emami, A Asadipour, A Shafiee… - European Journal of …, 2015 - Elsevier
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …

Visible light photocatalysis in the synthesis of pharmaceutically relevant heterocyclic scaffolds

V Srivastava, PK Singh, S Tivari… - Organic Chemistry …, 2022 - pubs.rsc.org
Visible light and photoredox catalysis have emerged as a powerful and long-lasting tool for
organic synthesis, demonstrating the importance of a variety of chemical bond formation …

Catalyst-free organic transformations under visible-light

M Tavakolian, M Hosseini-Sarvari - ACS Sustainable Chemistry & …, 2021 - ACS Publications
Pollutants from industry and chemical laboratories have harmful effects on human health
and the environment. Concerns about this problem have led to the development of more …

Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2, 4-disubstituted thiazole ring

SK Bharti, G Nath, R Tilak, SK Singh - European journal of medicinal …, 2010 - Elsevier
A series of arylidene-2-(4-(4-methoxy/bromophenyl) thiazol-2-yl) hydrazines (4a–z) and 1-(4-
(4-methoxy/bromophenyl) thiazol-2-yl)-2-cyclohexylidene/cyclopentylidene hydrazines (5a …

Thiazoles: having diverse biological activities

SJ Kashyap, VK Garg, PK Sharma, N Kumar… - Medicinal Chemistry …, 2012 - Springer
In the last few decades, a lot of work has been done on thiazole ring to find new compounds
related to this scaffold to act as antioxidant, analgesic, anti-inflammatory, antimicrobial …

Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives

MH Shih, FY Ke - Bioorganic & medicinal chemistry, 2004 - Elsevier
3-Aryl-4-formylsydnone 4′-phenylthiosemicarbazones (3a–d) and 3-aryl-4-formylsydnone
thiosemicarbazones (3e–h), which are precursors of 3-aryl-4-heterocyclic sydnones, are …

Synthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene) hydrazinyl] thiazole-4-carboxylate

M Haroon, T Akhtar, M Yousuf, MN Tahir, L Rasheed… - BMC chemistry, 2022 - Springer
Abstract The ethyl 2-[2-(2-nitrobenzylidene) hydrazinyl] thiazole-4-carboxylate (1), a thiazole
ester, was synthesized by refluxing 1-(2-nitrobenzylidene) thiosemicarbazide and ethyl …

[PDF][PDF] Thiazoles: a valuable insight into the recent advances and biological activities

N Siddiqui, MF Arshad, W Ahsan… - Int. J. Pharm. Sci. Drug …, 2009 - researchgate.net
Thiazoles displayed broad range of biological activities and found in many potent
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …

Synthesis of some novel 2, 4-disubstituted thiazoles as possible antimicrobial agents

P Karegoudar, MS Karthikeyan, DJ Prasad… - European Journal of …, 2008 - Elsevier
A series of novel 4-aryl/chloroalkyl-2-(2, 3, 5-trichlorophenyl)-1, 3-thiazoles (5a–g and 7a–e)
were synthesized by condensing 2, 3, 5-trichlorobenzenecarbothioamide with phenacyl …

Convenient one pot synthesis of some novel derivatives of thiazolo [2, 3-b] dihydropyrimidinone possessing 4-methylthiophenyl moiety and evaluation of their …

M Ashok, BS Holla, NS Kumari - European journal of medicinal chemistry, 2007 - Elsevier
A series of new 2-(arylidene/5-arylfurfurylidene)-5-(4-methylthiophenyl)-6-carbethoxy-7-
methyl-5H-thiazolo [2, 3-b] pyrimidin-3 (1H)-ones 2 and 3 have been synthesized by a three …