Visualization of omics data for systems biology

N Gehlenborg, SI O'donoghue, NS Baliga… - Nature …, 2010 - nature.com
High-throughput studies of biological systems are rapidly accumulating a wealth of'omics'-
scale data. Visualization is a key aspect of both the analysis and understanding of these …

Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future

GA Pavlopoulos, D Malliarakis, N Papanikolaou… - …, 2015 - academic.oup.com
Abstract “Α picture is worth a thousand words.” This widely used adage sums up in a few
words the notion that a successful visual representation of a concept should enable easy …

Escher: a web application for building, sharing, and embedding data-rich visualizations of biological pathways

ZA King, A Dräger, A Ebrahim… - PLoS computational …, 2015 - journals.plos.org
Escher is a web application for visualizing data on biological pathways. Three key features
make Escher a uniquely effective tool for pathway visualization. First, users can rapidly …

Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary

X Mao, T Cai, JG Olyarchuk, L Wei - Bioinformatics, 2005 - academic.oup.com
Motivation: High-throughput technologies such as DNA sequencing and microarrays have
created the need for automated annotation of large sets of genes, including whole genomes …

A systems biology approach for pathway level analysis

S Draghici, P Khatri, AL Tarca, K Amin, A Done… - Genome …, 2007 - genome.cshlp.org
A common challenge in the analysis of genomics data is trying to understand the underlying
phenomenon in the context of all complex interactions taking place on various signaling …

Pathway Tools version 19.0 update: software for pathway/genome informatics and systems biology

PD Karp, M Latendresse, SM Paley… - Briefings in …, 2016 - academic.oup.com
Pathway Tools is a bioinformatics software environment with a broad set of capabilities. The
software provides genome-informatics tools such as a genome browser, sequence …

KOBAS server: a web-based platform for automated annotation and pathway identification

J Wu, X Mao, T Cai, J Luo, L Wei - Nucleic acids research, 2006 - academic.oup.com
There is an increasing need to automatically annotate a set of genes or proteins (from
genome sequencing, DNA microarray analysis or protein 2D gel experiments) using …

Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology

PD Karp, SM Paley, M Krummenacker… - Briefings in …, 2010 - academic.oup.com
Pathway Tools is a production-quality software environment for creating a type of model-
organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc …

The ocean sampling day consortium

A Kopf, M Bicak, R Kottmann, J Schnetzer, I Kostadinov… - Gigascience, 2015 - Springer
Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Bioinformatics applications for pathway analysis of microarray data

T Werner - Current opinion in biotechnology, 2008 - Elsevier
Changes in transcript levels are assessed by microarray analysis on an individual basis,
essentially resulting in long lists of genes that were found to have significantly changed …