The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Structural diversity and species distribution of host-defense peptides in frog skin secretions

JM Conlon - Cellular and Molecular Life Sciences, 2011 - Springer
Cationic peptides that adopt an amphipathic α-helical conformation in a membrane-mimetic
environment are synthesized in the skins of many frog species. These peptides often display …

[PDF][PDF] Medical microbiology

GF Brooks, JS Butel, SA Morse - United States, 25th, 2006 - academia.edu
The book's purpose is to introduce basic clinical microbiology through the fields of
bacteriology, virology, mycology, and parasitology to provide a brief, accurate, and up to …

The contribution of skin antimicrobial peptides to the system of innate immunity in anurans

JM Conlon - Cell and tissue research, 2011 - Springer
Cationic peptides with the propensity to adopt an amphipathic α-helical conformation in a
membrane-mimetic environment are synthesized in the skins of many species of anurans …

d-Amino acids in antimicrobial peptides: a potential approach to treat and combat antimicrobial resistance

S Kapil, V Sharma - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Antimicrobial resistance is one of the leading challenges in the human healthcare segment.
Advances in antimicrobial resistance have triggered exploration of natural alternatives to …

Strategies for transformation of naturally-occurring amphibian antimicrobial peptides into therapeutically valuable anti-infective agents

JM Conlon, N Al-Ghaferi, B Abraham, J Leprince - Methods, 2007 - Elsevier
The emergence of strains of pathogenic microorganisms with resistance to commonly used
antibiotics has necessitated a search for novel types of antimicrobial agents. Many frog …

Computational design of highly selective antimicrobial peptides

D Juretic, D Vukicevic, N Ilic, N Antcheva… - Journal of chemical …, 2009 - ACS Publications
We have created a structure-selectivity database (AMPad) of frog-derived, helical
antimicrobial peptides (AMPs), in which the selectivity was determined as a therapeutic …

Insight into the mechanism of action of temporin-SHa, a new broad-spectrum antiparasitic and antibacterial agent

Z Raja, S André, F Abbassi, V Humblot, O Lequin… - PLoS …, 2017 - journals.plos.org
Antimicrobial peptides (AMPs) are promising drugs to kill resistant pathogens. In contrast to
bacteria, protozoan parasites, such as Leishmania, were little studied. Therefore, the …

Glycine‐replaced epinecidin‐1 variant bestows better stability and stronger antimicrobial activity against a range of nosocomial pathogenic bacteria

S Jeyarajan, AS Peter, S Ranjith… - Biotechnology and …, 2024 - Wiley Online Library
Abstract Epinecidin‐1 (epi‐1), an antimicrobial peptide first identified in marine grouper fish,
has multifunctional bioactivities. The present study aims to improve its therapeutic potential …

Imcroporin, a New Cationic Antimicrobial Peptide from the Venom of the Scorpion Isometrus maculates

Z Zhao, Y Ma, C Dai, R Zhao, SR Li, Y Wu… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The pace of resistance against antibiotics almost exceeds that of the development of new
drugs. As many bacteria have become resistant to conventional antibiotics, new drugs or …