Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours

C Horbinski, T Berger, RJ Packer, PY Wen - Nature Reviews Neurology, 2022 - nature.com
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

Clinical practice guidelines for the management of adult diffuse gliomas

T Jiang, DH Nam, Z Ram, W Poon, J Wang… - Cancer letters, 2021 - Elsevier
To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …

WHO 2016 Classification of gliomas

P Wesseling, D Capper - Neuropathology and applied …, 2018 - Wiley Online Library
Gliomas are the most frequent intrinsic tumours of the central nervous system and
encompass two principle subgroups: diffuse gliomas and gliomas showing a more …

Central nervous system cancers, version 3.2020, NCCN clinical practice guidelines in oncology

LB Nabors, J Portnow, M Ahluwalia, J Baehring… - Journal of the National …, 2020 - jnccn.org
The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of
adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas …

Isocitrate dehydrogenase (IDH) mutant gliomas: a Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions

JJ Miller, LN Gonzalez Castro, S McBrayer… - Neuro …, 2023 - academic.oup.com
Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant
primary brain tumors diagnosed in patients younger than 50, constituting an important cause …

Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis

Q Cui, K Yin, X Zhang, P Ye, X Chen, J Chao, H Meng… - Nature cancer, 2021 - nature.com
Pseudouridine is the most frequent epitranscriptomic modification. However, its cellular
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …

The epidemiology of glioma in adults: a “state of the science” review

QT Ostrom, L Bauchet, FG Davis, I Deltour… - Neuro …, 2014 - academic.oup.com
Gliomas are the most common primary intracranial tumor, representing 81% of malignant
brain tumors. Although relatively rare, they cause significant mortality and morbidity …

IDH1 and IDH2 Mutations in Gliomas

AL Cohen, SL Holmen, H Colman - Current neurology and neuroscience …, 2013 - Springer
Mutations in isocitrate dehydrogenase (IDH) 1 and 2, originally discovered in 2008, occur in
the vast majority of low-grade gliomas and secondary high-grade gliomas. These mutations …

Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications

TM Malta, CF de Souza, TS Sabedot, TC Silva… - Neuro …, 2018 - academic.oup.com
Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical
properties. Despite advances in surgical techniques and clinical regimens, treatment of high …