The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field

G Coorey, GA Figtree, DF Fletcher, VJ Snelson… - NPJ digital …, 2022 - nature.com
Potential benefits of precision medicine in cardiovascular disease (CVD) include more
accurate phenotyping of individual patients with the same condition or presentation, using …

Left Ventricular Thrombus Following Acute Myocardial Infarction: JACC State-of-the-Art Review

A Camaj, V Fuster, G Giustino, SW Bienstock… - Journal of the American …, 2022 - jacc.org
The incidence of left ventricular (LV) thrombus following acute myocardial infarction has
markedly declined in recent decades caused by advancements in reperfusion and …

Traditional Chinese medicine compound (Tongxinluo) and clinical outcomes of patients with acute myocardial infarction: the CTS-AMI randomized clinical trial

Y Yang, X Li, G Chen, Y Xian, H Zhang, Y Wu, Y Yang… - Jama, 2023 - jamanetwork.com
Importance Tongxinluo, a traditional Chinese medicine compound, has shown promise in in
vitro, animal, and small human studies for myocardial infarction, but has not been rigorously …

Mental stress and cardiovascular health—part I

F Vancheri, G Longo, E Vancheri… - Journal of clinical medicine, 2022 - mdpi.com
Epidemiological studies have shown that a substantial proportion of acute coronary events
occur in individuals who lack the traditional high-risk cardiovascular (CV) profile. Mental …

Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: results from a global meta-analysis of 1,285,722 patients

G Kong, YH Chin, B Chong, RSJ Goh, OZH Lim… - International Journal of …, 2023 - Elsevier
Background Standard modifiable cardiovascular risk factors (SMuRF), comprising diabetes,
hyperlipidemia, hypertension, and smoking, are used for risk stratification in acute coronary …

Flow-mediated dilation reference values for evaluation of endothelial function and cardiovascular health

C Heiss, A Rodriguez-Mateos, M Bapir… - Cardiovascular …, 2023 - academic.oup.com
Aims Endothelial function is essential for cardiovascular health, and flow-mediated dilation
(FMD) is an established technique to measure it. This paper aims to assess FMD values in …

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review

GA Figtree, ST Vernon, JA Harmer, MP Gray… - Journal of the American …, 2023 - jacc.org
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors
(SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD) …

[HTML][HTML] Treatment strategies of acute myocardial infarction: updates on revascularization, pharmacological therapy, and beyond

Y Saito, K Oyama, K Tsujita, S Yasuda, Y Kobayashi - Journal of cardiology, 2023 - Elsevier
Owing to recent advances in early reperfusion strategies, pharmacological therapy,
standardized care, and the identification of vulnerable patient subsets, the prognosis of …

Prognostic outcomes in acute myocardial infarction patients without standard modifiable risk factors: a multiethnic study of 8,680 Asian patients

G Kong, NWS Chew, CH Ng, YH Chin… - Frontiers in …, 2022 - frontiersin.org
Background An increasing proportion of patients with acute myocardial infarction (AMI) are
presenting without standard modifiable risk factors (SMuRFs) of hypertension …

Noninvasive plaque imaging to accelerate coronary artery disease drug development

GA Figtree, PD Adamson, C Antoniades… - Circulation, 2022 - Am Heart Assoc
Coronary artery disease (CAD) remains the leading cause of adult mortality globally.
Targeting known modifiable risk factors has had substantial benefit, but there remains a …