Mycobacterium tuberculosis possesses a dynamic cell envelope, which consists of a
peptidoglycan layer, a mycolic acid layer, and an arabinogalactan polysaccharide. This …

Mycobacterium tuberculosis (Mtb) is the etiological agent of tuberculosis (TB), a disease
that, although preventable and curable, remains a global epidemic due to the emergence of …

Increasing evidence supports the repositioning of beta-lactams for tuberculosis (TB) therapy,
but further research on their interaction with conventional anti-TB agents is still warranted …

Rising antimicrobial resistance challenges our ability to combat bacterial infections. The
problem is acute for tuberculosis (TB), the leading cause of death from infection before …

Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb),
infects 10 million people a year. An estimated 25% of humans harbor latent TB infections, an …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains the
leading cause of death from an infectious bacterium and is responsible for 1.8 million deaths …

Activity-based protein profiling (ABPP) is a powerful chemical approach for probing protein
function and enzymatic activity in complex biological systems. This strategy typically utilizes …

Abstract Bacterial chaperones ClpB and DnaK, homologs of the respective eukaryotic heat
shock proteins Hsp104 and Hsp70, are essential in the reactivation of toxic protein …

Chronic tuberculosis (TB) disease, which requires months-long chemotherapy with multiple
antibiotics, is defined by diverse pathological manifestations and bacterial phenotypes …

Bacteria comprise complex communities within our bodies and largely have beneficial roles,
however a small percentage are pathogenic. While all pathogens are important to public …