Deformability is an essential feature of blood cells (RBCs) that enables them to travel
through even the smallest capillaries of the human body. Deformability is a function of (i) …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Cold static preservation on ice (~ 4° C) remains the clinical standard of donor organ
preservation. However, mitochondrial injury develops during prolonged storage, which limits …

Hypoxia triggers a wide range of protective responses in mammalian cells, which are
mediated through transcriptional and post-translational mechanisms. Redox signaling in …

Traumatic brain injury (TBI) is a leading cause of death and disability in young adults
worldwide. TBI survival is associated with persistent neuropsychiatric and neurological …

Hypoxia is a state of reduced oxygen supply and excessive oxygen consumption. According
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …

Intracellular signaling mechanisms in red blood cells (RBCs) involve various protein kinases
and phosphatases and enable rapid adaptive responses to hypoxia, metabolic …

Na/K-ATPase has been extensively studied for its ion pumping function, but, in the past
several decades, has been identified as a scaffolding and signaling protein. Initially it was …

Introduction Ischemic stroke is one of the leading causes of death worldwide. Recently,
neuroprotection is regarded as an important preventative and therapeutic strategy for …

Our aim is to present an updated overview of the erythrocyte metabolism highlighting its
richness and complexity. We have manually collected and connected the available …