Coronary atherosclerosis is by far the most frequent cause of ischemic heart disease, and
plaque disruption with superimposed thrombosis is the main cause of the acute coronary …

Women with the metabolic syndrome (central obesity, insulin resistance, and dyslipidemia)
are known to be at especially high risk for cardiovascular disease (CVD). The prevalence of …

Background Inflammation may be important in the pathogenesis of atherothrombosis. We
studied whether inflammation increases the risk of a first thrombotic event and whether …

Background—Interleukin-6 (IL-6) plays a central role in inflammation and tissue injury.
However, epidemiological data evaluating the role of IL-6 in atherogenesis are sparse …

Objective: To summarise quantitatively the association between moderate alcohol intake
and biological markers of risk of coronary heart disease and to predict how these changes …

Background The intercellular adhesion molecule ICAM-1 mediates adhesion and
transmigration of leucocytes to the vascular endothelial wall, a step proposed to be critical in …

Various psychosocial factors have been implicated in the etiology and pathogenesis of
certain cardiovascular diseases such as atherosclerosis, now considered to be the result of …

The subject of neuroinflammation is reviewed. In response to psychological stress or certain
physical stressors, an inflammatory process may occur by release of neuropeptides …

Background Increased levels of certain hemostatic factors may play a part in the
development of acute coronary syndromes and may be associated with an increased risk of …

Background A specific point mutation in the gene coding for coagulation factor V is
associated with resistance to degradation by activated protein C, a recently described …