Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

L Brown, JM Wolf, R Prados-Rosales… - Nature Reviews …, 2015 - nature.com
Extracellular vesicles (EVs) are produced by all domains of life. In Gram-negative bacteria,
EVs are produced by the pinching off of the outer membrane; however, how EVs escape the …

A comprehensive review of signal peptides: Structure, roles, and applications

H Owji, N Nezafat, M Negahdaripour… - European journal of cell …, 2018 - Elsevier
Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …

Manufacturing of human extracellular vesicle-based therapeutics for clinical use

M Gimona, K Pachler, S Laner-Plamberger… - International journal of …, 2017 - mdpi.com
Extracellular vesicles (EVs) derived from stem and progenitor cells may have therapeutic
effects comparable to their parental cells and are considered promising agents for the …

Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis

P Nicolas, U Mäder, E Dervyn, T Rochat, A Leduc… - Science, 2012 - science.org
Bacteria adapt to environmental stimuli by adjusting their transcriptomes in a complex
manner, the full potential of which has yet to be established for any individual bacterial …

Lipases for biotechnology

KE Jaeger, T Eggert - Current opinion in biotechnology, 2002 - Elsevier
Lipases constitute the most important group of biocatalysts for biotechnological applications.
The high-level production of microbial lipases requires not only the efficient overexpression …

Feature-based prediction of non-classical and leaderless protein secretion

JD Bendtsen, LJ Jensen, N Blom… - Protein Engineering …, 2004 - academic.oup.com
We present a sequence-based method, SecretomeP, for the prediction of mammalian
secretory proteins targeted to the non-classical secretory pathway, ie proteins without an N …

Overview of bacterial expression systems for heterologous protein production: from molecular and biochemical fundamentals to commercial systems

K Terpe - Applied microbiology and biotechnology, 2006 - Springer
During the proteomics period, the growth in the use of recombinant proteins has increased
greatly in the recent years. Bacterial systems remain most attractive due to low cost, high …

Bacterial cell attachment, the beginning of a biofilm

J Palmer, S Flint, J Brooks - Journal of Industrial Microbiology …, 2007 - academic.oup.com
The ability of bacteria to attach to surfaces and develop into a biofilm has been of
considerable interest to many groups in numerous industries, including the medical and …

Phytoplasmas: bacteria that manipulate plants and insects

SA Hogenhout, K Oshima, ELD AMMAR… - Molecular plant …, 2008 - Wiley Online Library
SUMMARY Taxonomy: Superkingdom Prokaryota; Kingdom Monera; Domain Bacteria;
Phylum Firmicutes (low‐G+ C, Gram‐positive eubacteria); Class Mollicutes; Candidatus …

Proteomics of Protein Secretion by Bacillus subtilis: Separating the “Secrets” of the Secretome

H Tjalsma, H Antelmann, JDH Jongbloed… - Microbiology and …, 2004 - Am Soc Microbiol
Secretory proteins perform a variety of important “remote-control” functions for bacterial
survival in the environment. The availability of complete genome sequences has allowed us …