Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …

Myeloid cells in tumor tissues constitute a dynamic immune population characterized by a
non-uniform phenotype and diverse functional activities. Both tumor-associated …

NK cells are the major lymphocyte subset of the innate immune system that mediates
antiviral and anti-tumor responses. It is well established that they develop mechanisms to …

Cross-talk between the tumor microenvironment (TME) and cancer cells plays an important
role in acquired drug resistance to epidermal growth factor receptor tyrosine kinase …

Immune cells, as a consequence of their plasticity, can acquire altered phenotype/functions
within the tumor microenvironment (TME). Some of these aberrant functions include …

The word “biocompatibility,” is inconsistent with the observations of healing for so‐called
biocompatible biomaterials. The vast majority of the millions of medical implants in humans …

Natural killer (NK) cells are pivotal effectors of the innate immunity protecting an individual
from microbes. They are the first line of defense against invading viruses, given their …

The tumor immune microenvironment (TIME) controls tumorigenesis. Neutrophils are
important components of TIME and control tumor progression and therapy resistance …