A new perspective on thyroid hormones: crosstalk with reproductive hormones in females

B Ren, Y Zhu - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence has shown that thyroid hormones (THs) are vital for female
reproductive system homeostasis. THs regulate the reproductive functions through thyroid …

The androgen-thyroid hormone crosstalk in prostate cancer and the clinical implications

S Torabinejad, C Miro, B Barone… - European thyroid …, 2023 - etj.bioscientifica.com
There is increasing evidence that thyroid hormones (THs) work in an integrative fashion with
androgen receptors (ARs) to regulate gonadal differentiation and reproductive function …

Superswelling microneedle arrays for dermal interstitial fluid (prote) omics

E Laszlo, G De Crescenzo… - Advanced Functional …, 2021 - Wiley Online Library
The noninvasive sampling of dermal interstitial fluid (ISF) for the monitoring of clinical
biomarkers is a greatly appealing area of research. The identification of molecular …

Thyroid hormone and androgen signals mutually interplay and enhance inflammation and tumorigenic activation of tumor microenvironment in prostate cancer

C Miro, A Di Giovanni, M Murolo, AG Cicatiello… - Cancer Letters, 2022 - Elsevier
Abstract Prostate Cancer (PCa) is the most commonly diagnosed non-cutaneous cancer in
males and the fifth leading cause of death worldwide. The majority of PCas are androgen …

Viral involvement in Alzheimer's disease

A Sait, C Angeli, AJ Doig, PJR Day - ACS chemical neuroscience, 2021 - ACS Publications
Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

circMine: a comprehensive database to integrate, analyze and visualize human disease–related circRNA transcriptome

W Zhang, Y Liu, Z Min, G Liang, J Mo, Z Ju… - Nucleic Acids …, 2022 - academic.oup.com
Many circRNA transcriptome data were deposited in public resources, but these data show
great heterogeneity. Researchers without bioinformatics skills have difficulty in investigating …

DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations

J Gallon, A Rodriguez-Calero, A Benjak… - Cancer research, 2023 - AACR
Metastases from primary prostate cancers to rare locations, such as the brain, are becoming
more common due to longer life expectancy resulting from improved treatments. Epigenetic …

Emerging role of T3-binding protein μ-crystallin (CRYM) in health and disease

O Aksoy, B Hantusch, L Kenner - Trends in Endocrinology & Metabolism, 2022 - cell.com
Thyroid hormones are essential metabolic and developmental regulators that exert a huge
variety of effects in different organs. Triiodothyronine (T3) and thyroxine (T4) are synthesized …

Phenomic imaging

L Lan, K Feng, Y Wu, W Zhang, L Wei, H Che, L Xue… - Phenomics, 2023 - Springer
Human phenomics is defined as the comprehensive collection of observable phenotypes
and characteristics influenced by a complex interplay among factors at multiple scales …

Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate …

Y Erzurumlu, MT Muhammed - Cellular Signalling, 2023 - Elsevier
Thyroid hormones (THs) play crucial roles in numerous physiological processes of nearly all
mammalian tissues, including differentiation and metabolism. Deterioration of TH signaling …