Purpose To develop a mathematical model for predicting shear-induced von Willebrand
factor (vWF) function modification which can be used to guide ventricular assist devices …

Objective Non-physiological shear stress (NPSS) and thrombin have two distinct
mechanisms for activating platelets. NPSS in mechanically assisted circulation (MAC) …

Extracorporeal life support (ECLS) includes life-saving support in severe acute cardiac
and/or pulmonary failure. In the past 20 years, centrifugal pumps have become the primary …

Accurate and fast prediction of the hemodynamics of the artificial pump-lung is critical in the
design process. In this study, a comprehensive computational framework, including a sliding …

We designed a photo-ECMO device to speed up the rate of carbon monoxide (CO) removal
by using visible light to dissociate CO from hemoglobin (Hb). Using computational fluid …

Abstract Background The Food and Drug Administration (FDA) blood pump is an open‐
source benchmark cardiovascular device introduced for validating computational and …

Systematic research into device-induced red blood cell (RBC) damage beyond hemolysis,
including correlations between hemolysis and RBC-derived extracellular vesicles, remains …

Background High mechanical shear stress (HMSS) generated by blood pumps during
mechanical circulatory support induces blood damage (or function alteration) not only of …

Blood pumps have become popular whether for use as an implantable ventricular assist
device or as extracorporeal membrane oxygenation. The quality of these pumps is assessed …

Thanks to recent technological and IT advances, there have been rapid developments in
biomedical and health research applications of computational fluid dynamics. This is a …