Brain protection in aortic arch surgery: an evolving field

JZ Qu, LW Kao, JE Smith, A Kuo, A Xue, MH Iyer… - … of Cardiothoracic and …, 2021 - Elsevier
Despite advances in cardiac surgery and anesthesia, the rates of brain injury remain high in
aortic arch surgery requiring circulatory arrest. The mechanisms of brain injury, including …

Hypothermic Circulatory Arrest in Adult Aortic Arch Surgery: A Review of Hypothermic Circulatory Arrest and its Anesthetic Implications

S Ghia, A Savadjian, DW Shin, G Diluozzo… - … of Cardiothoracic and …, 2023 - jcvaonline.com
Diseases affecting the aortic arch often require surgical intervention. Hypothermic circulatory
arrest (HCA) enables a safe approach during open aortic arch surgeries. Additionally, HCA …

Moderate and deep hypothermic circulatory arrest has a comparable effect on acute kidney injury after total arch replacement with frozen elephant trunk procedure in …

Z Fang, G Wang, Q Liu, H Zhou, S Zhou… - Interactive …, 2019 - academic.oup.com
OBJECTIVES The goal was to investigate the prevalence of acute kidney injury (AKI) after
total arch replacement with frozen elephant trunk procedure, which was achieved by …

Gene-modified exosomes protect the brain against prolonged deep hypothermic circulatory arrest

J Shi, X Jiang, S Gao, Y Zhu, J Liu, T Gu… - The Annals of Thoracic …, 2021 - Elsevier
Background Neurologic deficit remains a major complication after cardiovascular surgeries
with deep hypothermic circulatory arrest (DHCA). We hypothesized that exosomes derived …

The use of blood and blood products in aortic surgery is associated with adverse outcomes

I Sultan, V Bianco, E Aranda-Michel, A Kilic… - The Journal of Thoracic …, 2023 - Elsevier
Objective To report long-term outcomes after deep hypothermic circulatory arrest (DHCA)
with or without perioperative blood or blood products. Methods All patients who underwent …

Clinical evaluation of a cutaneous zero-heat-flux thermometer during cardiac surgery

C Verheyden, A Neyrinck, A Laenen, S Rex… - Journal of Clinical …, 2022 - Springer
We evaluated the disposable non-invasive SpotOn™ thermometer relying on the zero-heat-
flux technology. We tested the hypothesis that this technology may accurately estimate the …

The effects of ATP on the contractions of rat and mouse fast skeletal muscle

AU Ziganshin, AE Khairullin, AY Teplov… - Muscle & …, 2019 - Wiley Online Library
Introduction: The aim of this study was to compare the effects of adenosine‐5'‐triphosphate
(ATP) and adenosine on the contractility of rodent extensor digitorum longus (EDL) muscle …

Ketamine mitigates neurobehavioral deficits in a canine model of hypothermic circulatory arrest

K Giuliano, E Etchill, AK Velez, MA Wilson… - Seminars in thoracic and …, 2023 - Elsevier
Hypothermic circulatory arrest is a protective technique used when complete cessation of
circulation is required during cardiac surgery. Prior efforts to decrease neurologic injury with …

Optimal cerebral protection strategies in aortic surgery

X Lou, EP Chen - Seminars in thoracic and cardiovascular surgery, 2019 - Elsevier
Cerebral protection strategies in aortic surgery have undergone significant evolution over
the years, but its tenets remain rooted in maintenance of hypothermia and cerebral perfusion …

Hybrid repair versus conventional open repair for thoracic aortic arch aneurysms

A Elhelali, N Hynes, D Devane, S Sultan… - Cochrane Database …, 2021 - cochranelibrary.com
Background Thoracic aortic arch aneurysms (TAAs) can be a life‐threatening condition due
to the potential risk of rupture. Treatment is recommended when the risk of rupture is greater …