The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza

XH Ma, Y Ma, JF Tang, YL He, YC Liu, XJ Ma, Y Shen… - Molecules, 2015 - mdpi.com
Secondary metabolites from plants play key roles in human medicine and chemical
industries. Due to limited accumulation of secondary metabolites in plants and their …

Yeast chronological lifespan: longevity regulatory genes and mechanisms

MG Mirisola, VD Longo - Cells, 2022 - mdpi.com
S. cerevisiae plays a pivotal role as a model system in understanding the biochemistry and
molecular biology of mammals including humans. A considerable portion of our knowledge …

Unveiling the impact of Aging on BBB and Alzheimer's disease: Factors and Therapeutic implications

VK Nelson, NK Jha, MV Nuli, S Gupta, S Kanna… - Ageing research …, 2024 - Elsevier
Alzheimer's disease (AD) is a highly prevalent neurodegenerative condition that has
devastating effects on individuals, often resulting in dementia. AD is primarily defined by the …

Longevity extension by phytochemicals

A Leonov, A Arlia-Ciommo, A Piano, V Svistkova… - Molecules, 2015 - mdpi.com
Phytochemicals are structurally diverse secondary metabolites synthesized by plants and
also by non-pathogenic endophytic microorganisms living within plants. Phytochemicals …

Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting …

K Guo, R Liu, R Jing, L Wang, X Li, K Zhang… - Frontiers in …, 2022 - frontiersin.org
The integrity of skin tissue structure and function plays an important role in maintaining skin
rejuvenation. Ultraviolet (UV) radiation is the main environmental factor that causes skin …

The Anti-Aging Potential of Neohesperidin and Its Synergistic Effects with Other Citrus Flavonoids in Extending Chronological Lifespan of Saccharomyces Cerevisiae …

C Guo, H Zhang, X Guan, Z Zhou - Molecules, 2019 - mdpi.com
The anti-aging activity of many plant flavonoids, as well as their mechanisms of action, have
been explored in the current literature. However, the studies on the synergistic effects …

Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa …

FS Senol, S Ślusarczyk, A Matkowski, A Pérez-Garrido… - Phytochemistry, 2017 - Elsevier
Cholinesterase inhibition is one of the most treatment strategies against Alzheimer's disease
(AD) where metal accumulation is also strongly associated with pathology of the disease. In …

Are polyphenols strong dietary agents against neurotoxicity and neurodegeneration?

S Almeida, MG Alves, M Sousa, PF Oliveira… - Neurotoxicity …, 2016 - Springer
Life expectancy of most human populations has greatly increased as a result of factors
including better hygiene, medical practice, and nutrition. Unfortunately, as humans age, they …

[HTML][HTML] The integrated stress response in budding yeast lifespan extension

SDL Postnikoff, JE Johnson, JK Tyler - Microbial Cell, 2017 - ncbi.nlm.nih.gov
Aging is a complex, multi-factorial biological process shared by all living organisms. It is
manifested by a gradual accumulation of molecular alterations that lead to the decline of …

Life-span extension by pigmented rice bran in the model yeast Saccharomyces cerevisiae

P Sunthonkun, R Palajai, P Somboon, CL Suan… - Scientific Reports, 2019 - nature.com
Benefits of whole grains as dietary supplements and active ingredients in health products
have been promoted. Despite being neglected as an agricultural byproduct of polished rice …