Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?
F Qiu, CL Liang, H Liu, YQ Zeng, S Hou, S Huang… - …, 2016 - pmc.ncbi.nlm.nih.gov
Cigarette smoking is associated with numerous diseases and poses a serious challenge to
the current healthcare system worldwide. Smoking impacts both innate and adaptive …
the current healthcare system worldwide. Smoking impacts both innate and adaptive …
The role of TLRs in neutrophil activation
Neutrophils are key innate immune effector cells that are rapidly recruited to sites of infection
and inflammation to provide early defence against invading microorganisms. This function is …
and inflammation to provide early defence against invading microorganisms. This function is …
Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice
SD Pouwels, GJ Zijlstra… - … of Physiology-Lung …, 2016 - journals.physiology.org
Recent data indicate a role for airway epithelial necroptosis, a regulated form of necrosis,
and the associated release of damage-associated molecular patterns (DAMPs) in the …
and the associated release of damage-associated molecular patterns (DAMPs) in the …
Airway epithelium dysfunction in cystic fibrosis and COPD
Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene, whereas chronic
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …
Implications of the immune landscape in COPD and lung cancer: smoking versus other causes
E Taucher, I Mykoliuk, J Lindenmann… - Frontiers in …, 2022 - frontiersin.org
Cigarette smoking is reported in about one third of adults worldwide. A strong relationship
between cigarette smoke exposure and chronic obstructive pulmonary disease (COPD) as …
between cigarette smoke exposure and chronic obstructive pulmonary disease (COPD) as …
[HTML][HTML] DAMPs activating innate and adaptive immune responses in COPD
SD Pouwels, IH Heijink, NH Ten Hacken… - Mucosal …, 2014 - Elsevier
Chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized
by sustained neutrophilic airway inflammation, is caused by chronic exposure to noxious …
by sustained neutrophilic airway inflammation, is caused by chronic exposure to noxious …
The role of HMGB1/RAGE/TLR4 signaling pathways in cigarette smoke‐induced inflammation in chronic obstructive pulmonary disease
L Lin, J Li, Q Song, W Cheng… - … inflammation and disease, 2022 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease
with irreversible and continuous progression. It has become the fifth most burdensome …
with irreversible and continuous progression. It has become the fifth most burdensome …
Lung antimicrobial proteins and peptides: From host defense to therapeutic strategies
YP Di, JM Kuhn, ML Mangoni - Physiological Reviews, 2024 - journals.physiology.org
Representing severe morbidity and mortality globally, respiratory infections associated with
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …
Toll like receptors in diseases of the lung
MA Kovach, TJ Standiford - International immunopharmacology, 2011 - Elsevier
The lung is in continuous contact with a diverse array of infectious agents, foreign antigens,
and host-derived danger signals. To sample this expansive internal and external milieu …
and host-derived danger signals. To sample this expansive internal and external milieu …
A synbiotic mixture of Bifidobacterium breve M16-V, oligosaccharides and pectin, enhances Short Chain Fatty Acid production and improves lung health in a …
GFG Bezemer, MAP Diks, E Mortaz, I van Ark… - Frontiers in …, 2024 - frontiersin.org
Introduction Pulmonary neutrophilia is a hallmark of numerous airway diseases including
Chronic Obstructive Pulmonary Disease (COPD), Neutrophilic asthma, Acute Lung Injury …
Chronic Obstructive Pulmonary Disease (COPD), Neutrophilic asthma, Acute Lung Injury …