Identification of clinically relevant biomarkers of epileptogenesis—a strategic roadmap
M Simonato, DV Agoston, A Brooks-Kayal… - Nature Reviews …, 2021 - nature.com
Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …
[HTML][HTML] PET studies in epilepsy
I Sarikaya - American journal of nuclear medicine and molecular …, 2015 - ncbi.nlm.nih.gov
Various PET studies, such as measurements of glucose, serotonin and oxygen metabolism,
cerebral blood flow and receptor bindings are availabe for epilepsy. 18 Fluoro-2 …
cerebral blood flow and receptor bindings are availabe for epilepsy. 18 Fluoro-2 …
A review of molecular imaging of glutamate receptors
JH Kim, J Marton, SM Ametamey, P Cumming - Molecules, 2020 - mdpi.com
Molecular imaging with positron emission tomography (PET) and single photon emission
computed tomography (SPECT) is a well-established and important in vivo technique to …
computed tomography (SPECT) is a well-established and important in vivo technique to …
Neuroimaging biomarkers of experimental epileptogenesis and refractory epilepsy
This article provides an overview of neuroimaging biomarkers in experimental
epileptogenesis and refractory epilepsy. Neuroimaging represents a gold standard and …
epileptogenesis and refractory epilepsy. Neuroimaging represents a gold standard and …
Recent developments in diagnosis of epilepsy: scope of MicroRNA and technological advancements
R Bandopadhyay, T Singh, MM Ghoneim, S Alshehri… - Biology, 2021 - mdpi.com
Simple Summary Through epilepsy is one of the leading causes of poor mental health,
increased school dropout, and socioeconomic burden, yet the diagnosis remains a …
increased school dropout, and socioeconomic burden, yet the diagnosis remains a …
Development of PET and SPECT probes for glutamate receptors
T Fuchigami, M Nakayama… - The Scientific World …, 2015 - Wiley Online Library
l‐Glutamate and its receptors (GluRs) play a key role in excitatory neurotransmission within
the mammalian central nervous system (CNS). Impaired regulation of GluRs has also been …
the mammalian central nervous system (CNS). Impaired regulation of GluRs has also been …
Imaging in Vivo Glutamate Fluctuations with [11C]ABP688: A GLT-1 Challenge with Ceftriaxone
Molecular imaging offers unprecedented opportunities for investigating dynamic changes
underlying neuropsychiatric conditions. Here, we evaluated whether [11C] ABP688, a …
underlying neuropsychiatric conditions. Here, we evaluated whether [11C] ABP688, a …
In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD
Although the pathogenesis underlying behavioral variant frontotemporal dementia (bvFTD)
has yet to be fully understood, glutamatergic abnormalities have been hypothesized to play …
has yet to be fully understood, glutamatergic abnormalities have been hypothesized to play …
Dynamic changes in striatal mGluR1 but not mGluR5 during pathological progression of Parkinson's disease in human alpha-synuclein A53T transgenic rats: a multi …
T Yamasaki, M Fujinaga, K Kawamura… - Journal of …, 2016 - Soc Neuroscience
Parkinson's disease (PD) is a prevalent degenerative disorder affecting the CNS that is
primarily characterized by resting tremor and movement deficits. Group I metabotropic …
primarily characterized by resting tremor and movement deficits. Group I metabotropic …
Abnormal metabolic connectivity in the pilocarpine-induced epilepsy rat model: a multiscale network analysis based on persistent homology
Temporal lobe epilepsy is associated with dysfunctional brain networks. Here we
investigated metabolic connectivity in the pilocarpine-induced epilepsy rat model and …
investigated metabolic connectivity in the pilocarpine-induced epilepsy rat model and …