[HTML][HTML] Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms

C Stonesifer, S Corey, S Ghanekar, Z Diamandis… - Progress in …, 2017 - Elsevier
Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis

A Bronckaers, P Hilkens, W Martens, P Gervois… - Pharmacology & …, 2014 - Elsevier
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Intrathecal transplantation of autologous adipose-derived mesenchymal stem cells for treating spinal cord injury: a human trial

JW Hur, TH Cho, DH Park, JB Lee, JY Park… - The Journal of Spinal …, 2016 - Taylor & Francis
Context: Spinal cord injury (SCI) can cause irreversible damage to neural tissues. However,
there is currently no effective treatment for SCI. The therapeutic potential of adipose-derived …

[HTML][HTML] Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle …

X Hu, J Pan, Y Li, Y Jiang, H Zheng, R Shi… - Stem Cell Research & …, 2022 - Springer
Background Adipose-derived stem cells (ADSCs) and their extracellular vesicles (EVs) have
therapeutic potential in ischemic brain injury, but the underlying mechanism is poorly …

Intracerebral transplantation of autologous adipose‐derived stem cells for chronic ischemic stroke: A phase I study

TL Chiu, R Baskaran, ST Tsai… - Journal of tissue …, 2022 - Wiley Online Library
Current therapy does not provide significant benefits for patients with chronic stroke. Pre‐
clinical studies suggested that autologous adipose‐derived stem cells have benefits for the …

[HTML][HTML] Long-term follow-up and exploration of the mechanism of stromal vascular fraction gel in chronic wounds

Y Cai, F Zhang, J Feng, B Wu, H Li, S Xiao, F Lu… - Stem Cell Research & …, 2023 - Springer
Background Chronic refractory wounds easily relapse and seriously affect the patients'
quality of life. Previous studies have shown that stromal vascular fraction gel (SVF-gel) …

Therapeutic potential of adipose stem cell‐derived conditioned medium against pulmonary hypertension and lung fibrosis

A Rathinasabapathy, E Bruce, A Espejo… - British Journal of …, 2016 - Wiley Online Library
Background and Purpose Pulmonary hypertension (PH) and pulmonary fibrosis (PF) are life
threatening cardiopulmonary diseases. Existing pharmacological interventions have failed …

In Vitro Oxygen‐Glucose Deprivation‐Induced Stroke Models with Human Neuroblastoma Cell‐ and Induced Pluripotent Stem Cell‐Derived Neurons

M Juntunen, S Hagman, A Moisan… - Stem cells …, 2020 - Wiley Online Library
Stroke is a devastating neurological disorder and one of the leading causes of mortality and
disability. To understand the cellular and molecular mechanisms of stroke and to develop …

[HTML][HTML] Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery …

F Zhou, S Gao, L Wang, C Sun, L Chen, P Yuan… - Stem cell research & …, 2015 - Springer
Introduction Growing evidence has brought stem cell therapy to the forefront as new
promising approaches towards stroke treatment. Of all candidate seeding cells, adipose …

Therapeutic potential of human adipose-derived stem cells in neurological disorders

KA Chang, JH Lee, YH Suh - Journal of pharmacological sciences, 2014 - jstage.jst.go.jp
Stem cell therapy has been noted as a novel strategy to various diseases including
neurological disorders such as Alzheimer's disease, Parkinson's disease, stroke …