Neurotransmitters: The critical modulators regulating gut–brain axis
R Mittal, LH Debs, AP Patel, D Nguyen… - Journal of cellular …, 2017 - Wiley Online Library
Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
Ion channels in innate and adaptive immunity
Ion channels and transporters mediate the transport of charged ions across hydrophobic
lipid membranes. In immune cells, divalent cations such as calcium, magnesium, and zinc …
lipid membranes. In immune cells, divalent cations such as calcium, magnesium, and zinc …
[HTML][HTML] B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
Small, soluble metabolites not only are essential intermediates in intracellular biochemical
processes, but can also influence neighbouring cells when released into the extracellular …
processes, but can also influence neighbouring cells when released into the extracellular …
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
D Huang, Y Wang, JW Thompson, T Yin… - Nature cell …, 2022 - nature.com
Many cancers have an unusual dependence on glutamine. However, most previous studies
have focused on the contribution of glutamine to metabolic building blocks and the energy …
have focused on the contribution of glutamine to metabolic building blocks and the energy …
Ion channels and transporters in lymphocyte function and immunity
S Feske, EY Skolnik, M Prakriya - Nature Reviews Immunology, 2012 - nature.com
Lymphocyte function is regulated by a network of ion channels and transporters in the
plasma membrane of B and T cells. These proteins modulate the cytoplasmic concentrations …
plasma membrane of B and T cells. These proteins modulate the cytoplasmic concentrations …
GABA and GABA receptors in the central nervous system and other organs
M Watanabe, K Maemura, K Kanbara… - International review of …, 2002 - Elsevier
γ-Aminobutyrate (GABA) is a major inhibitory neurotransmitter in the adult mammalian brain.
GABA is also considered to be a multifunctional molecule that has different situational …
GABA is also considered to be a multifunctional molecule that has different situational …
Inhibitory role for GABA in autoimmune inflammation
R Bhat, R Axtell, A Mitra, M Miranda… - Proceedings of the …, 2010 - National Acad Sciences
GABA, the principal inhibitory neurotransmitter in the adult brain, has a parallel inhibitory
role in the immune system. We demonstrate that immune cells synthesize GABA and have …
role in the immune system. We demonstrate that immune cells synthesize GABA and have …
[HTML][HTML] Immune proteins in brain development and synaptic plasticity
LM Boulanger - Neuron, 2009 - cell.com
Many proteins first identified in the immune system are also expressed in the developing
and adult nervous system. Unexpectedly, recent studies reveal that a number of these …
and adult nervous system. Unexpectedly, recent studies reveal that a number of these …
[HTML][HTML] Pharmacotherapy for status epilepticus
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
GABA and GABA receptors in the gastrointestinal tract: from motility to inflammation
M Auteri, MG Zizzo, R Serio - Pharmacological research, 2015 - Elsevier
Although an extensive body of literature confirmed γ-aminobutyric acid (GABA) as mediator
within the enteric nervous system (ENS) controlling gastrointestinal (GI) function, the true …
within the enteric nervous system (ENS) controlling gastrointestinal (GI) function, the true …