Although computational modeling is common in many areas of science and engineering,
only recently have advances in experimental techniques and medical imaging allowed this …

Ventricular wall stress is believed to be responsible for many physical mechanisms taking
place in the human heart, including ventricular remodeling, which is frequently associated …

Predictive computational modelling in biomedical research offers the potential to integrate
diverse data, uncover biological mechanisms that are not easily accessible through …

Injectable biomaterials are an attractive therapy to attenuate left ventricular (LV) remodeling
after myocardial infarction (MI). Although studies have shown that injectable hydrogels …

A central problem in biomechanical studies of personalized human left ventricular (LV)
modelling is to estimate material properties from in vivo clinical measurements. In this work …

An unresolved issue in patients with diastolic dysfunction is that the estimation of myocardial
stiffness cannot be decoupled from diastolic residual active tension (AT) because of the …

BACKGROUND: Left ventricular remodeling after posterobasal myocardial infarction can
lead to ischemic mitral regurgitation. This occurs as a consequence of leaflet tethering due …

In this research, we hypothesized that novel biomechanical parameters are discriminative in
patients following acute ST-segment elevation myocardial infarction (STEMI). To identify …

Parameter estimation from non-invasive measurements is a crucial step in patient-specific
cardiac modeling. It also has the potential to provide significant assistance in the clinical …

Progressive stiffening of collagen tissue by bioapatite mineral is important physiologically,
but the details of this stiffening are uncertain. Unresolved questions about the details of the …